Introduction The roles of metabolic signals, including Glucagon-like peptide 1 (GLP-1), have
been implicated in multiple domains outside metabolic regulation. There is a growing …

The orexin/hypocretin neuropeptide family has emerged as a focal point of neuroscientific
research following the discovery that this family plays a crucial role in a variety of …

Circadian clocks control most physiological processes of many species. We specifically
wanted to investigate the influence of environmental and endogenous rhythms and their …

Maintaining proper circadian rhythms is essential for coordinating biological functions in
mammals. This study investigates the effects of daily arrhythmicity using Bmal1-knockout …

Pain behavior and the systems that mediate opioid analgesia and opioid reward processing
display circadian rhythms. Moreover, the pain system and opioid processing systems …

How dopamine signaling regulates biological rhythms is an area of emerging interest. Here
we review experiments focused on delineating dopamine signaling in the suprachiasmatic …

Primary cilia are cellular appendages critical for diverse types of Signaling. They are found
on most cell types, including cells throughout the CNS. Cilia preferentially localize certain G …

Level of motivation, responsiveness to rewards and punishment, invigoration of exploratory
behaviours, and motor performance are subject to daily fluctuations that emerge from …

The suprachiasmatic nucleus (SCN) is the main region for the regulation of circadian
rhythms. Although the SCN contains a heterogeneous neurochemical phenotype with a …

Circadian rhythms are internal manifestations of the 24-h solar day that allow for
synchronization of biological and behavioral processes to the external solar day. This …