Digital Recombinase Polymerase Amplification, Digital Loop‐Mediated Isothermal Amplification, and Digital CRISPR‐Cas Assisted Assay: Current Status, Challenges …

W Yin, J Zhuang, J Li, L **a, K Hu, J Yin, Y Mu - Small, 2023 - Wiley Online Library
Digital nucleic acid detection based on microfluidics technology can quantify the initial
amount of nucleic acid in the sample with low equipment requirements and simple …

Rapid on-site nucleic acid testing: On-chip sample preparation, amplification, and detection, and their integration into all-in-one systems

J Wang, H Jiang, L Pan, X Gu, C **ao, P Liu… - … in Bioengineering and …, 2023 - frontiersin.org
As nucleic acid testing is playing a vital role in increasingly many research fields, the need
for rapid on-site testing methods is also increasing. The test procedure often consists of …

The recent advances of high-throughput biosensors for rapid detection of foodborne pathogens

Y Zhao, Y Shang, Z Wang, Z Wang, J **e, H Zhai… - TrAC Trends in …, 2024 - Elsevier
Foodborne diseases, induced by various foodborne pathogens, have emerged as an urgent
global health concern. The establishment of prompt, precise, and expeditious detection …

UV-Assisted hyperbranched poly (β-amino ester) modification of a silica membrane for two-step microfluidic DNA extraction from blood

A Jagannath, Y Li, H Cong, J Hassan… - … Applied Materials & …, 2023 - ACS Publications
Integrating nucleic acid extraction in amplification-based point-of-care diagnostics will be a
significant feature for next-generation point-of-care virus detection devices. However …

Polyaniline-based 3D network structure promotes entrapment and detection of drug-resistant bacteria

Y Song, N Park, DA Jo, J Kim, D Yong, J Song… - Nano …, 2023 - Springer
Sensitive and accurate capture, enrichment, and identification of drug-resistant bacteria on
human skin are important for early-stage diagnosis and treatment of patients. Herein, we …

A cost-effective and field-deployable sensing system for chip-integrated detection of bacteria with the naked eye

R Shen, W Hui, W Wu, N Yang, X Lin, PI Mak… - Sensors and Actuators B …, 2024 - Elsevier
To tailor the broadly applied polymerase chain reaction (PCR) technology to point-of-care
settings, an intuitive, time-saving, and cost-effective method to determine the DNA …

A magnet-actuated microfluidic array chip for high-throughput pretreatment and amplification and detection of multiple pathogens

M Zhou, H Su, B Wang, C Wan, W Du, P Chen, X Feng… - Analyst, 2022 - pubs.rsc.org
The outbreak of global infectious diseases has posed a significant threat to public health,
requiring the rapid and accurate diagnosis of pathogens promptly for the society to …

Tackling the issue of healthcare associated infections through point-of-care devices

A Canciu, A Cernat, M Tertis, F Graur… - TrAC Trends in Analytical …, 2023 - Elsevier
The rapid diagnosis of bacterial strains is paramount for the management of healthcare
associated infections (HAIs) and combating the antimicrobial resistance (AMR), two of the …

Nanotopology‐Enabled On‐Site Pathogen Detection for Managing Atopic Dermatitis

S Kim, Y Song, J Kim, B Jeong, N Park… - Advanced …, 2024 - Wiley Online Library
Atopic dermatitis (AD), a prevalent skin condition often complicated by microbial infection,
poses a significant challenge in identifying the responsible pathogen for its effective …

Automated Microfluidic Systems Facilitating the Scalable and Reliable Production of Lipid Nanoparticles for Gene Delivery

D Jung, S Jang, D Park, NH Bae, CS Han, S Ryu… - BioChip Journal, 2024 - Springer
Lipid nanoparticles have become a promising agent for biocompatible, effective, stable, and
clinically approved delivery system that protect the nucleic acid from degradation while …