Exosomes are common membrane-bound nanovesicles that contain diverse biomolecules,
such as lipids, proteins, and nucleic acids. Exosomes are derived from cells through …

Discovered in the late 1980s as an extracellular vesicle of endosomal origin secreted from
reticulocytes, exosomes recently gained scientific attention due to its role in intercellular …

Digested dietary fats are taken up by enterocytes where they are assembled into pre-
chylomicrons in the endoplasmic reticulum followed by transport to the Golgi for maturation …

The endomembrane system consists of organellar membranes in the biosynthetic pathway
[endoplasmic reticulum (ER), Golgi apparatus, and secretory vesicles] as well as those in the …

Exosomes are small membrane vesicles that are secreted by a multitude of cell types as a
consequence of fusion of multivesicular late endosomes/lysosomes with the plasma …

Eosinophils are pleiotropic multifunctional leukocytes involved in initiation and propagation
of diverse inflammatory responses, as well as modulators of innate and adaptive immunity …

During reticulocyte maturation, some membrane proteins and organelles that are not
required in the mature red cell are lost. Several of these proteins are released into the …

Neutrophils are critical inflammatory cells that cause tissue damage in a range of diseases
and disorders. Being bone marrow-derived white blood cells, they migrate from the …

Hypospadias results from a failure of urethral closure in the male phallus and affects 1 in
200-300 boys. It is thought to be due to a combination of genetic and environmental factors …

The online version of this article contains supplemental material. Address correspondence
to Sanford M. Simon, Laboratory of Cellular Biophysics, Rockefeller University, Box 304 …