Ruthenium (II) polypyridyl complexes and DNA—from structural probes to cellular imaging and therapeutics
In the last few decades, coordination complexes based on d6 metal centres and polypyridyl
ligand architectures been developed as structure-and site-specific reversible DNA binding …
ligand architectures been developed as structure-and site-specific reversible DNA binding …
Anticancer activity of metal complexes: involvement of redox processes
U Jungwirth, CR Kowol, BK Keppler, CG Hartinger… - 2011 - liebertpub.com
Cells require tight regulation of the intracellular redox balance and consequently of reactive
oxygen species for proper redox signaling and maintenance of metal (eg, of iron and …
oxygen species for proper redox signaling and maintenance of metal (eg, of iron and …
Rhodium (III)–Picolinamide Complexes Act as Anticancer and Antimetastasis Agents via Inducing Apoptosis and Autophagy
YQ Gu, K Yang, QY Yang, HQ Li, MQ Hu… - Journal of Medicinal …, 2023 - ACS Publications
As a continuation of our endeavors in discovering metal-based drugs with cytotoxic and
antimetastatic activities, herein, we reported the syntheses of 11 new rhodium (III) …
antimetastatic activities, herein, we reported the syntheses of 11 new rhodium (III) …
Bioactive iridium and rhodium complexes as therapeutic agents
CH Leung, HJ Zhong, DSH Chan, DL Ma - Coordination Chemistry …, 2013 - Elsevier
Group 9 metal complexes based on iridium and rhodium have recently arisen as fascinating
potential alternatives to existing platinum and ruthenium metallodrugs. While long regarded …
potential alternatives to existing platinum and ruthenium metallodrugs. While long regarded …
[HTML][HTML] The role of surface functionality on acute cytotoxicity, ROS generation and DNA damage by cationic gold nanoparticles
A Chompoosor, K Saha, PS Ghosh… - Small (Weinheim an …, 2010 - ncbi.nlm.nih.gov
Gold nanoparticles (AuNPs) are promising materials for biomedical applications [1, 2] due to
their tunable surface properties [3] and extraordinary stability.[4] Additionally, the inert core …
their tunable surface properties [3] and extraordinary stability.[4] Additionally, the inert core …
DNA/protein binding, molecular docking, and in vitro anticancer activity of some thioether-dipyrrinato complexes
Syntheses and characterizations of the arene ruthenium [(η6-C6H6) RuCl (4-mtdpm)](1),[(η6-
p-MeC6H4Pri) RuCl (4-mtdpm)](2), and structurally analogous rhodium/iridium complexes …
p-MeC6H4Pri) RuCl (4-mtdpm)](2), and structurally analogous rhodium/iridium complexes …
Recent development of copper (II) complexes of polypyridyl ligands in chemotherapy and photodynamic therapy
Cancer is a deadly disease associated with abnormal cell growth and invasion to various
parts of the body. Many drugs such as cisplatin and carboplatin have been used for the …
parts of the body. Many drugs such as cisplatin and carboplatin have been used for the …
Synthesis, antiproliferative activity and apoptosis-promoting effects of arene ruthenium (II) complexes with N, O chelating ligands
New half sandwich arene ruthenium (II) complexes of the type [Ru (arene) Cl (L)](where
arene= benzene and p-cymene, L= thiophene benzhydrazone ligands) have been …
arene= benzene and p-cymene, L= thiophene benzhydrazone ligands) have been …
DNA binding and anti-cancer activity of redox-active heteroleptic piano-stool Ru (II), Rh (III), and Ir (III) complexes containing 4-(2-methoxypyridyl) …
The synthesis of four novel heteroleptic dipyrrinato complexes [(η6-arene) RuCl (2-
pcdpm)](η6-arene= C6H6, 1; C10H14, 2) and [(η5-C5Me5) MCl (2-pcdpm)](M= Rh, 3; Ir, 4) …
pcdpm)](η6-arene= C6H6, 1; C10H14, 2) and [(η5-C5Me5) MCl (2-pcdpm)](M= Rh, 3; Ir, 4) …
[Ru(bpy)2(5-cyanouracil)2]2+ as a Potential Light-Activated Dual-Action Therapeutic Agent
RN Garner, JC Gallucci, KR Dunbar… - Inorganic Chemistry, 2011 - ACS Publications
The cation cis-[Ru (bpy) 2 (5CNU) 2] 2+(bpy= 2, 2′-bipyridine; 5CNU= 5-cyanouracil) was
synthesized and investigated for use as a potential light-activated dual-action therapeutic …
synthesized and investigated for use as a potential light-activated dual-action therapeutic …