[HTML][HTML] Mesoporous silica nanoparticles for therapeutic/diagnostic applications

S Jafari, H Derakhshankhah, L Alaei, A Fattahi… - Biomedicine & …, 2019 - Elsevier
Based on unique intrinsic properties of mesoporous silica nanoparticles (MSNs) such as
high surface area, large pore size, good biocompatibility and biodegradability, stable …

CURATE. AI: optimizing personalized medicine with artificial intelligence

A Blasiak, J Khong, T Kee - … TECHNOLOGY: Translating Life …, 2020 - journals.sagepub.com
The clinical team attending to a patient upon a diagnosis is faced with two main questions:
what treatment, and at what dose? Clinical trials' results provide the basis for guidance and …

Highly efficient hydrogel encapsulation of hydrophobic drugs via an organic solvent-free process based on oiling-out crystallization and a mechanism study

M Sun, M Gao, J Bi, Y Zhao, J Gong - ACS Sustainable Chemistry …, 2024 - ACS Publications
Hydrogel encapsulation of hydrophobic drugs is challenging because the hydrophilic nature
of hydrogel is highly likely to result in a low loading efficiency (LE), and complex …

Crystallization and Polymorphism under Nanoconfinement

N Fellah, IJC Dela Cruz, BG Alamani… - Crystal Growth & …, 2024 - ACS Publications
Crystallization outcomes, polymorph stability rankings, and phase transformation pathways
can be significantly altered when crystallization is restricted to dimensions below 1 μm. In …

[HTML][HTML] Multimodal decorations of mesoporous silica nanoparticles for improved cancer therapy

S Barui, V Cauda - Pharmaceutics, 2020 - mdpi.com
The presence of leaky vasculature and the lack of lymphatic drainage of small structures by
the solid tumors formulate nanoparticles as promising delivery vehicles in cancer therapy. In …

Fabrication of basil oil Nanoemulsion loaded gellan gum hydrogel—Evaluation of its antibacterial and anti-biofilm potential

SK Chinnaiyan, R Pandiyan, S Natesan… - Journal of Drug Delivery …, 2022 - Elsevier
The pathogenic suppression of infectious agents is an ongoing strategy to tackle threats
from microbial infections. In this regard, we developed and characterized a stable basil oil …

[書籍][B] Nanoparticles for biomedical applications: fundamental concepts, biological interactions and clinical applications

EJ Chung, L Leon, C Rinaldi - 2019 - books.google.com
Nanoparticles for Biomedical Applications: Fundamental Concepts, Biological Interactions
and Clinical Applications brings into one place information on the design and biomedical …

Theoretical and Experimental Determinations of the Hydrophilic–Lipophilic Balance (HLB) of Representative Oils and Lecithins

G Smejkal, V Gross, A Lazarev - Colloids and Interfaces, 2024 - mdpi.com
The hydrophilic–lipophilic balance (HLB) is a valuable parameter used to determine the
relative hydrophobicity of a compound based on its chemical structure. This semi-empirical …

[HTML][HTML] Development and characterization of nanoemulsions for ophthalmic applications: Role of cationic surfactants

AR Fernandes, E Sanchez-Lopez, T Santos, ML Garcia… - Materials, 2021 - mdpi.com
The eye is a very complex organ comprising several physiological and physical barriers that
compromise drug absorption into deeper layers. Nanoemulsions are promising delivery …

Process intensification for pharmaceutical crystallization

J Wang, F Li, R Lakerveld - Chemical Engineering and Processing-Process …, 2018 - Elsevier
Process intensification (PI) provides great opportunities to drastically improve the
performance of chemical processes within many branches of chemical industry including the …