Nucleation, map** and control of cavitation for drug delivery

E Stride, C Coussios - Nature Reviews Physics, 2019 - nature.com
Acoustically driven bubbles produce a range of mechanical, thermal and chemical effects
that can be exploited in drug delivery applications. Significant improvements in the targeting …

[HTML][HTML] Pancreatic ductal adenocarcinoma: Current and emerging therapeutic uses of focused ultrasound

M Lafond, T Lambin, RA Drainville, A Dupré, M Pioche… - Cancers, 2022 - mdpi.com
Simple Summary Pancreatic ductal adenocarcinoma (PDAC) is an increasingly prevalent
form of cancer with a low patient survival rate following diagnosis. Focused Ultrasound is an …

Initiating and imaging cavitation from infused echo contrast agents through the EkoSonic catheter

SR Kennedy, M Lafond, KJ Haworth, DS Escudero… - Scientific reports, 2023 - nature.com
Ultrasound-enhanced delivery of therapeutic-loaded echogenic liposomes is under
development for vascular applications using the EkoSonic Endovascular System. In this …

Quantifying the effect of acoustic parameters on temporal and spatial cavitation activity: gauging cavitation dose

DS Escudero, KJ Haworth, C Genstler… - Ultrasound in medicine & …, 2023 - Elsevier
Objective Cavitation-enhanced delivery of therapeutic agents is under development for the
treatment of cancer and neurodegenerative and cardiovascular diseases, including …

Volumetric Passive Acoustic Map** and Cavitation Detection of Nanobubbles under Low-Frequency Insonation

H Shinar, T Ilovitsh - ACS Materials Au, 2024 - ACS Publications
Gas bubbles, commonly used in medical ultrasound (US), witness advancements with
nanobubbles (NB), providing improved capabilities over microbubbles (MB). NBs offer …

Real-time passive acoustic map** using sparse matrix multiplication

HAS Kamimura, SY Wu, J Grondin, R Ji… - IEEE transactions on …, 2020 - ieeexplore.ieee.org
Passive acoustic map** enables the spatiotemporal monitoring of cavitation with
circulating microbubbles during focused ultrasound (FUS)-mediated blood–brain barrier …

Dual-array passive acoustic map** for cavitation imaging with enhanced 2-D resolution

MD Gray, D Elbes, C Paverd, E Lyka… - IEEE Transactions …, 2020 - ieeexplore.ieee.org
Passive acoustic map** (PAM) techniques have been developed for the purposes of
detecting, localizing, and quantifying cavitation activity during therapeutic ultrasound …

Passive acoustic map** using data-adaptive beamforming based on higher order statistics

E Lyka, CM Coviello, C Paverd, MD Gray… - IEEE transactions on …, 2018 - ieeexplore.ieee.org
Sources of nonlinear acoustic emissions, particularly those associated with cavitation
activity, play a key role in the safety and efficacy of current and emerging therapeutic …

Assessment of collaborative robot (cobot)-assisted histotripsy for venous clot ablation

KB Bader, SA Hendley, V Bollen - IEEE Transactions on …, 2020 - ieeexplore.ieee.org
Objective: The application of bubble-based ablation with the focus ultrasound therapy
histotripsy is gaining traction for the treatment of venous thrombosis, among other …

Broadband ultrasonic attenuation estimation and compensation with passive acoustic map**

MD Gray, CC Coussios - IEEE Transactions on Ultrasonics …, 2018 - ieeexplore.ieee.org
Several active and passive techniques have been developed to detect, localize, and
quantify cavitation activity during therapeutic ultrasound procedures. Much of the prior …