Psoriasis is an immune-mediated genetic skin disease. The underlying pathomechanisms
involve complex interaction between the innate and adaptive immune system. T cells …

Progress in understanding of the mechanisms underlying chronic inflammatory skin
disorders, such as atopic dermatitis and psoriasis vulgaris, has led to new treatment options …

Whereas the cellular and molecular features of human inflammatory skin diseases are well
characterized, their tissue context and systemic impact remain poorly understood. We thus …

Background Tildrakizumab is a high-affinity, humanised, IgG1 κ antibody targeting
interleukin 23 p19 that represents an evolving treatment strategy in chronic plaque psoriasis …

Psoriasis has long been known as a disease with many complications, but was attributed to
diet and obesity. However, in recent years, psoriasis itself has been recognized as a series …

Biological therapy became available for psoriasis with the introduction of alefacept at the
beginning of this century. Up to then, systemic treatment options comprised small molecule …

Psoriasis is a common chronic inflammatory skin disease with a complex pathogenesis
consisting of a genetic component, immune dysfunction, and environmental factors. It is …

Hyperhomocysteinemia is recognized as a risk factor for several diseases, including
cardiovascular and neurological conditions. Homocysteine (HCys) is a key metabolite …

Psoriasis is a chronic systemic inflammatory disorder associated with several comorbidities
in addition to the characteristic skin lesions. Metabolic syndrome (MetS) is the most frequent …

Objective: Psoriasis is an inflammatory skin disease affecting 2–4% of the world population.
The objective of this study was to perform a systematic review and meta-analysis …