Boron delivery agents for neutron capture therapy of cancer

RF Barth, P Mi, W Yang - Cancer Communications, 2018 - Springer
Boron neutron capture therapy (BNCT) is a binary radiotherapeutic modality based on the
nuclear capture and fission reactions that occur when the stable isotope, boron-10, is …

Boron agents for neutron capture therapy

K Hu, Z Yang, L Zhang, L **e, L Wang, H Xu… - Coordination Chemistry …, 2020 - Elsevier
Boron neutron capture therapy (BNCT) is a potential cancer radiotherapeutic modality,
which takes advantage of the neutron capture response that occurs when boron (10 B) is …

Boron encapsulated in a liposome can be used for combinational neutron capture therapy

J Li, Q Sun, C Lu, H **ao, Z Guo, D Duan… - Nature …, 2022 - nature.com
Boron neutron capture therapy (BNCT) is an attractive approach to treat invasive malignant
tumours due to binary heavy-particle irradiation, but its clinical applications have been …

A critical review of radiation therapy: from particle beam therapy (proton, carbon, and BNCT) to beyond

Y Matsumoto, N Fukumitsu, H Ishikawa… - Journal of personalized …, 2021 - mdpi.com
In this paper, we discuss the role of particle therapy—a novel radiation therapy (RT) that has
shown rapid progress and widespread use in recent years—in multidisciplinary treatment …

Multiplexed imaging for diagnosis and therapy

K Heinzmann, LM Carter, JS Lewis… - Nature Biomedical …, 2017 - nature.com
Complex molecular and metabolic phenotypes depict cancers as a constellation of different
diseases with common themes. Precision imaging of such phenotypes requires flexible and …

Boron Vehiculating Nanosystems for Neutron Capture Therapy in Cancer Treatment

G Ailuno, A Balboni, G Caviglioli, F Lai, F Barbieri… - Cells, 2022 - mdpi.com
Boron neutron capture therapy is a low-invasive cancer therapy based on the neutron fission
process that occurs upon thermal neutron irradiation of 10B-containing compounds; this …

The dawn of a new era: tumor-targeting boron agents for neutron capture therapy

T Luo, W Huang, F Chu, T Zhu, B Feng… - Molecular …, 2023 - ACS Publications
Cancer is widely recognized as one of the most devastating diseases, necessitating the
development of intelligent diagnostic techniques, targeted treatments, and early prognosis …

Gadolinium neutron capture therapy (GdNCT) agents from molecular to nano: Current status and perspectives

SL Ho, H Yue, T Tegafaw, MY Ahmad, S Liu… - ACS …, 2022 - ACS Publications
157Gd (natural abundance= 15.7%) has the highest thermal neutron capture cross section
(σ) of 254,000 barns (1 barn= 10–28 m2) among stable (nonradioactive) isotopes in the …

Hybrid calcium phosphate-polymeric micelles incorporating gadolinium chelates for imaging-guided gadolinium neutron capture tumor therapy

P Mi, N Dewi, H Yanagie, D Kokuryo, M Suzuki… - ACS …, 2015 - ACS Publications
Gadolinium (Gd) chelates-loaded nanocarriers have high potential for achieving magnetic
resonance imaging (MRI)-guided Gd neutron capture therapy (GdNCT) of tumors. Herein …

Engineering novel targeted boron‐10‐enriched theranostic nanomedicine to combat against murine brain tumors via MR imaging‐guided boron neutron capture …

N Kuthala, R Vankayala, YN Li, CS Chiang… - Advanced …, 2017 - Wiley Online Library
Glioblastoma multiforme (GBM) is a very common type of “incurable” malignant brain tumor.
Although many treatment options are currently available, most of them eventually fail due to …