Does the epithelial barrier hypothesis explain the increase in allergy, autoimmunity and other chronic conditions?
CA Akdis - Nature Reviews Immunology, 2021 - nature.com
There has been a steep increase in allergic and autoimmune diseases, reaching epidemic
proportions and now affecting more than one billion people worldwide. These diseases are …
proportions and now affecting more than one billion people worldwide. These diseases are …
Gut microbiota and dysbiosis in Alzheimer's disease: implications for pathogenesis and treatment
S Liu, J Gao, M Zhu, K Liu, HL Zhang - Molecular neurobiology, 2020 - Springer
Understanding how gut flora influences gut-brain communications has been the subject of
significant research over the past decade. The broadening of the term “microbiota-gut-brain …
significant research over the past decade. The broadening of the term “microbiota-gut-brain …
Meta-analysis of the Parkinson's disease gut microbiome suggests alterations linked to intestinal inflammation
The gut microbiota is emerging as an important modulator of neurodegenerative diseases,
and accumulating evidence has linked gut microbes to Parkinson's disease (PD) …
and accumulating evidence has linked gut microbes to Parkinson's disease (PD) …
Gut microbiome composition may be an indicator of preclinical Alzheimer's disease
Alzheimer's disease (AD) pathology is thought to progress from normal cognition through
preclinical disease and ultimately to symptomatic AD with cognitive impairment. Recent work …
preclinical disease and ultimately to symptomatic AD with cognitive impairment. Recent work …
The progress of gut microbiome research related to brain disorders
There is increasing evidence showing that the dynamic changes in the gut microbiota can
alter brain physiology and behavior. Cognition was originally thought to be regulated only by …
alter brain physiology and behavior. Cognition was originally thought to be regulated only by …
Gut–brain axis: role of gut microbiota on neurological disorders and how probiotics/prebiotics beneficially modulate microbial and immune pathways to improve brain …
K Suganya, BS Koo - International journal of molecular sciences, 2020 - mdpi.com
The gut microbiome acts as an integral part of the gastrointestinal tract (GIT) that has the
largest and vulnerable surface with desirable features to observe foods, nutrients, and …
largest and vulnerable surface with desirable features to observe foods, nutrients, and …
The intestinal barrier in disorders of the central nervous system
C Pellegrini, M Fornai, V D'Antongiovanni… - The lancet …, 2023 - thelancet.com
The intestinal barrier, which primarily consists of a mucus layer, an epithelial barrier, and a
gut vascular barrier, has a crucial role in health and disease by facilitating nutrient …
gut vascular barrier, has a crucial role in health and disease by facilitating nutrient …
Oral administration of resveratrol-selenium-peptide nanocomposites alleviates Alzheimer's disease-like pathogenesis by inhibiting Aβ aggregation and regulating gut …
C Li, N Wang, G Zheng, L Yang - ACS Applied Materials & …, 2021 - ACS Publications
Alzheimer's disease (AD) is a neurodegenerative disease associated with amyloid-β (Aβ)
deposition, leading to neurotoxicity (oxidative stress and neuroinflammation) and gut …
deposition, leading to neurotoxicity (oxidative stress and neuroinflammation) and gut …
[HTML][HTML] The potential mechanism of postoperative cognitive dysfunction in older people
X Lin, Y Chen, P Zhang, G Chen, Y Zhou, X Yu - Experimental gerontology, 2020 - Elsevier
Postoperative cognitive dysfunction (POCD) is a common disorder following surgery, which
seriously threatens the quality of patients' life, especially the older people. Accumulating …
seriously threatens the quality of patients' life, especially the older people. Accumulating …
Metal drugs and the anticancer immune response
B Englinger, C Pirker, P Heffeter, A Terenzi… - Chemical …, 2018 - ACS Publications
The immune system deploys a multitude of innate and adaptive mechanisms not only to
ward off pathogens but also to prevent malignant transformation (“immune surveillance”) …
ward off pathogens but also to prevent malignant transformation (“immune surveillance”) …