The involvement of inflammasomes in the proinflammatory response observed in chronic
liver diseases, such as alcohol-associated liver disease (ALD) and nonalcoholic fatty liver …

Goblet cells and the mucus they secrete serve as an important barrier, preventing pathogens
from invading the mucosa to cause intestinal inflammation. The perspective regarding goblet …

Inflammasome complexes and their integral receptor proteins have essential roles in
regulating the innate immune response and inflammation at the post-translational level. Yet …

Aims Although highly heritable, the genetic etiology of calcific aortic stenosis (AS) remains
incompletely understood. The aim of this study was to discover novel genetic contributors to …

Oxidative stress is a major contributor to the pathogenesis of various inflammatory diseases.
Accumulating evidence has shown that oxidative stress is characterized by the …

Simple Summary The gut microbiome affects the development of systemic immune response
and it can also impact response to systemic treatments such as immunotherapy and …

The inflammasome is a protein complex composed of a variety of proteins in cells and which
participates in the innate immune response of the body. It can be activated by upstream …

Metastasis remains the primary cause of small cell lung cancer (SCLC)-related deaths.
Growing evidence links tumor metastasis with a pre-metastatic microenvironment …

Inflammasome activation is exclusively involved in sensing activation of innate immunity and
inflammatory response during viral infection. Accumulating evidence suggests that the …

Inflammasome is a cytoplasmic multiprotein complex that facilitates the clearance of
exogenous microorganisms or the recognition of endogenous danger signals, which is …