Methods and advances for monitoring neurotransmitters in vivo or for tissue analysis of
neurotransmitters over the last five years are reviewed. The review is organized primarily by …

The intracellular levels and spatial localizations of metabolites and peptides reflect the state
of a cell and its relationship to its surrounding environment. Moreover, the amounts and …

Live single-cell mass spectrometry (live MS) provides a mass spectrum that shows
thousands of metabolite peaks from a single live plant cell within minutes. By using an …

Matrix-assisted laser desorption/ionization (MALDI) mass spectrometry (MS) is one of the
most widely used techniques in proteomics to achieve structural identification and …

The chemical differences between individual cells within large cellular populations provide
unique information on organisms' homeostasis and the development of diseased states …

Molecular analysis at cellular and subcellular levels, whether on selected molecules or at
the metabolomics scale, is still a challenge now. Here we propose a method based on probe …

Cells are the most basic structural units that play vital roles in the functioning of living
organisms. Analysis of the chemical composition and content of a single cell plays a vital …

Mass spectrometry imaging and profiling of individual cells and subcellular structures
provide unique analytical capabilities for biological and biomedical research, including …

Simple Summary This review discusses the heterogeneity of breast cancer and strategies to
understand it using multi-omics profiling methods at the traditional bulk and single-cell …

Single-cell analysis (SCA) has been increasingly recognized as the key technology for the
elucidation of cellular functions, which are not accessible from bulk measurements on the …