Pharmacologic analgesia and sedation in neonates

C McPherson, RE Grunau - Clinics in Perinatology, 2022 - perinatology.theclinics.com
The past 4 decades have witnessed enormous leaps in understanding of the acute and long-
term impacts of neonatal pain and stress. Healthy infants experience roughly 12 skin …

Experience of early-life pain in premature infants is associated with atypical cerebellar development and later neurodevelopmental deficits

KM Cook, J De Asis-Cruz, JH Kim, SK Basu… - BMC medicine, 2023 - Springer
Background Infants born very and extremely premature (V/EPT) are at a significantly
elevated risk for neurodevelopmental disorders and delays even in the absence of structural …

Early-life exposure to analgesia and 18-month neurodevelopmental outcomes in very preterm infants

T Selvanathan, P Zaki, MA McLean, SH Au-Young… - Pediatric …, 2023 - nature.com
Background We assessed variability of analgesic use across three tertiary neonatal
intensive care units (NICUs) accounting for early-life pain, quantified as number of invasive …

Thalamic volume in very preterm infants: associations with severe brain injury and neurodevelopmental outcome at two years

E Trimarco, B Jafrasteh, N Jiménez-Luque… - Frontiers in …, 2024 - frontiersin.org
Introduction Several studies demonstrate the relationship between preterm birth and a
reduced thalamus volume at term-equivalent age. In contrast, this study aims to investigate …

[HTML][HTML] The influence of very preterm birth on adolescent EEG connectivity, network organization and long-term outcome

C van't Westende, ES Twilhaar, CJ Stam… - Clinical …, 2023 - Elsevier
Objective The aim of this study was to explore differences in functional connectivity and
network organization between very preterm born adolescents and term born controls and to …

Longitudinal functional brain connectivity maturation in premature newborn infants: Modulatory influence of early music enrichment

A Van Der Veek, S Loukas, L Lordier… - Imaging …, 2024 - direct.mit.edu
Premature birth affects brain maturation, illustrated by altered brain functional connectivity at
term equivalent age (TEA) and alters neurobehavioral outcome. To correct early …

[HTML][HTML] Neurodevelopmental disorders: 2021 update

A Zamora-Moratalla, MM de Lagrán… - Free …, 2021 - ncbi.nlm.nih.gov
One of the current challenges in the field of neurodevelopmental disorders (NDDs) is still to
determine their underlying aetiology and risk factors. NDDs comprise a diverse group of …

Brain Injury and Pain Exposure are Associated with Alterations in Structural Connectivity and Neurodevelopment in Very Preterm Infants

T Selvanathan - 2023 - search.proquest.com
Preterm infants undergo neonatal intensive care during a period of maturation of structural
brain networks, which may be affected by clinical illness and exposures such as brain injury …