Single-cell transcriptomic approaches are revolutionizing neuroscience. Integrating this
wealth of data with morphology and physiology, for the comprehensive study of neuronal …

Understanding the diversity of cell types in the brain has been an enduring challenge and
requires detailed characterization of individual neurons in multiple dimensions. To …

The mammalian brain is composed of diverse, specialized cell populations. To
systematically ascertain and learn from these cellular specializations, we used Drop-seq to …

The brain is an organ of immense complexity. Next-generation RNA sequencing (RNA-seq)
is becoming increasingly popular in the deconstruction of this complexity into distinct classes …

To understand the cellular basis of behavior, it is necessary to know the cell types that exist
in the nervous system and their contributions to function. Spinal networks are essential for …

Regulation of gene expression drives protein interactions that govern synaptic wiring and
neuronal activity. The resulting coordinated activity among neuronal populations supports …

Complex cognitive functions such as working memory and decision-making require
information maintenance over seconds to years, from transient sensory stimuli to long-term …

Establishing the molecular diversity of cell types is crucial for the study of the nervous
system. We compiled a cross-laboratory database of mouse brain cell type-specific …

Systematic spatial variation in micro-architecture is observed across the cortex. These micro-
architectural gradients are reflected in neural activity, which can be captured by …

Background Alzheimer's disease (AD) is a neurodegenerative disease associated with
widespread disruptions in intrinsic local specialization and global integration in the …