As the prevalence of obesity continues to rise, the world is facing a major public health
concern. Obesity is a complex disease associated with an increase in several inflammatory …

The prevalence of obesity is rapidly increasing globally. Epidemiological studies have
associated obesity with a range of cancer types, although the mechanisms by which obesity …

There is a constant high demand for energy to sustain the continuous contractile activity of
the heart, which is met primarily by the β-oxidation of long-chain fatty acids. The control of …

Background Insulin resistance appears to be the best predictor of the development of
diabetes in the children of patients with type 2 diabetes, but the mechanism responsible is …

Besides its role as an energy storage organ, adipose tissue can be viewed as a dynamic
and complex endocrine organ, which produces and secretes several adipokines, including …

Obesity is rampant in the United States and is becoming increasing common worldwide. The
increase in obesity prevalence is due to two major factors, plentiful supplies of inexpensive …

Adiponectin has recently been shown to be a promising candidate for the treatment of
obesity-associated metabolic syndromes. Replenishment of recombinant adiponectin in …

To examine the mechanism by which moderate weight reduction improves basal and insulin-
stimulated rates of glucose metabolism in patients with type 2 diabetes, we used 1H …

The prevalence of obesity is a major cause of many chronic metabolic disorders, including
type 2 diabetes mellitus (T2DM), cardiovascular disease (CVD), and cancer. Insulin …

We have identified Wnt10b as a potent inhibitor of adipogenesis that must be suppressed for
preadipocytes to differentiate in vitro. Here, we demonstrate that a specific inhibitor of …