A central goal of systems biology is to elucidate the structural and functional architecture of
the cell. To this end, large and complex networks of molecular interactions are being rapidly …

Disease–gene association through genome-wide association study (GWAS) is an arduous
task for researchers. Investigating single nucleotide polymorphisms that correlate with …

Discovering disease-gene association is a fundamental and critical biomedical task, which
assists biologists and physicians to discover pathogenic mechanism of syndromes. With …

Background: Identifying disease genes from human genome is an important but challenging
task in biomedical research. Machine learning methods can be applied to discover new …

Identifying disease–gene associations is a fundamental and critical biomedical task towards
understanding molecular mechanisms, the diagnosis and treatment of diseases. It is time …

Despite the widespread use of Arabidopsis (Arabidopsis thaliana) as a model plant, a
curated dataset of Arabidopsis genes with mutant phenotypes remains to be established. A …

An increasing number of genes have been experimentally confirmed in recent years as
causative genes to various human diseases. The newly available knowledge can be …

With the continuing development and improvement of genome-wide techniques, a great
number of candidate genes are discovered. How to identify the most likely disease genes …

Stress is perhaps easiest to conceptualize as a process which allows an organism to
accommodate for the demands of its environment such that it can adapt to the prevailing set …

Motivation To better predict and analyze gene associations with the collection of phenotypes
organized in a phenotype ontology, it is crucial to effectively model the hierarchical structure …