Human coronaviruses and other respiratory viruses: underestimated opportunistic pathogens of the central nervous system?

M Desforges, A Le Coupanec, P Dubeau, A Bourgouin… - viruses, 2019 - mdpi.com
Respiratory viruses infect the human upper respiratory tract, mostly causing mild diseases.
However, in vulnerable populations, such as newborns, infants, the elderly and immune …

Chikungunya fever

K Bartholomeeusen, M Daniel, DA LaBeaud… - Nature Reviews …, 2023 - nature.com
Chikungunya virus is widespread throughout the tropics, where it causes recurrent
outbreaks of chikungunya fever. In recent years, outbreaks have afflicted populations in East …

Chemical and biomolecular strategies for STING pathway activation in cancer immunotherapy

KM Garland, TL Sheehy, JT Wilson - Chemical reviews, 2022 - ACS Publications
The stimulator of interferon genes (STING) cellular signaling pathway is a promising target
for cancer immunotherapy. Activation of the intracellular STING protein triggers the …

[HTML][HTML] A review on chikungunya virus epidemiology, pathogenesis and current vaccine development

TYV de Lima Cavalcanti, MR Pereira, SO de Paula… - Viruses, 2022 - mdpi.com
Chikungunya virus (CHIKV) is a mosquito-borne alphavirus that recently re-emerged in
many parts of the world causing large-scale outbreaks. CHIKV infection presents as a febrile …

Chikungunya virus and the global spread of a mosquito-borne disease

SC Weaver, M Lecuit - New England Journal of Medicine, 2015 - Mass Medical Soc
Chikungunya virus infection is a rapid-onset, febrile disease with intense asthenia,
arthralgia, myalgia, headache, and rash. This mosquito-borne alphavirus has spread …

Severe acute respiratory syndrome coronavirus infection causes neuronal death in the absence of encephalitis in mice transgenic for human ACE2

J Netland, DK Meyerholz, S Moore, M Cassell… - Journal of …, 2008 - journals.asm.org
Infection of humans with the severe acute respiratory syndrome coronavirus (SARS-CoV)
results in substantial morbidity and mortality, with death resulting primarily from respiratory …

Chikungunya virus: epidemiology, replication, disease mechanisms, and prospective intervention strategies

LA Silva, TS Dermody - The Journal of clinical investigation, 2017 - jci.org
Chikungunya virus (CHIKV), a reemerging arbovirus, causes a crippling musculoskeletal
inflammatory disease in humans characterized by fever, polyarthralgia, myalgia, rash, and …

Identification of a candidate therapeutic autophagy-inducing peptide

S Shoji-Kawata, R Sumpter, M Leveno, GR Campbell… - Nature, 2013 - nature.com
The lysosomal degradation pathway of autophagy has a crucial role in defence against
infection, neurodegenerative disorders, cancer and ageing. Accordingly, agents that induce …

Zika, chikungunya, and other emerging vector-borne viral diseases

SC Weaver, C Charlier, N Vasilakis… - Annual review of …, 2018 - annualreviews.org
Arthropod-borne viruses (arboviruses) have a long history of emerging to infect humans, but
during recent decades, they have been spreading more widely and affecting larger …

Chikungunya fever: epidemiology, clinical syndrome, pathogenesis and therapy

SD Thiberville, N Moyen, L Dupuis-Maguiraga… - Antiviral research, 2013 - Elsevier
Chikungunya virus (CHIKV) is the aetiological agent of the mosquito-borne disease
chikungunya fever, a debilitating arthritic disease that, during the past 7 years, has caused …