Peptidomics

R Hellinger, A Sigurdsson, W Wu… - Nature Reviews …, 2023 - nature.com
Peptides are biopolymers, typically consisting of 2–50 amino acids. They are biologically
produced by the cellular ribosomal machinery or by non-ribosomal enzymes and …

Peptide design principles for antimicrobial applications

MDT Torres, S Sothiselvam, TK Lu… - Journal of molecular …, 2019 - Elsevier
The increased incidence of bacterial resistance to available antibiotics represents a major
global health problem and highlights the need for novel anti-infective therapies …

Conotoxins: chemistry and biology

AH **, M Muttenthaler, S Dutertre, SWA Himaya… - Chemical …, 2019 - ACS Publications
The venom of the marine predatory cone snails (genus Conus) has evolved for prey capture
and defense, providing the basis for survival and rapid diversification of the now estimated …

[КНИГА][B] Biology and evolution of the mollusca, volume 1

WF Ponder, DR Lindberg, JM Ponder - 2019 - taylorfrancis.com
Molluscs comprise the second largest phylum of animals (after arthropods), occurring in
virtually all habitats. Some are commercially important, a few are pests and some carry …

Cysteines and disulfide bonds as structure-forming units: insights from different domains of life and the potential for characterization by NMR

C Wiedemann, A Kumar, A Lang… - Frontiers in …, 2020 - frontiersin.org
Disulfide bridges establish a fundamental element in the molecular architecture of proteins
and peptides which are involved eg, in basic biological processes or acting as toxins. NMR …

Discovery, synthesis, and structure–activity relationships of conotoxins

KB Akondi, M Muttenthaler, S Dutertre, Q Kaas… - Chemical …, 2014 - ACS Publications
Peptide therapeutics are acclaimed as a promising addition to the pharmaceutical arena,
and they continue to attract interest due to their high potency, bioavailability, and fewer …

Introducing BASE: the Biomes of Australian Soil Environments soil microbial diversity database

A Bissett, A Fitzgerald, T Meintjes, PM Mele, F Reith… - GigaScience, 2016 - Springer
Background Microbial inhabitants of soils are important to ecosystem and planetary
functions, yet there are large gaps in our knowledge of their diversity and ecology. The …

Evolution of separate predation-and defence-evoked venoms in carnivorous cone snails

S Dutertre, AH **, I Vetter, B Hamilton… - Nature …, 2014 - nature.com
Venomous animals are thought to inject the same combination of toxins for both predation
and defence, presumably exploiting conserved target pharmacology across prey and …

An updated review on food‐derived bioactive peptides: Focus on the regulatory requirements, safety, and bioavailability

PJ Patil, M Usman, C Zhang… - … Reviews in Food …, 2022 - Wiley Online Library
Food‐derived bioactive peptides (BAPs) are recently utilized as functional food raw
materials owing to their potential health benefits. Although there is a huge amount of …

Informatics and computational methods in natural product drug discovery: a review and perspectives

JD Romano, NP Tatonetti - Frontiers in genetics, 2019 - frontiersin.org
The discovery of new pharmaceutical drugs is one of the preeminent tasks—scientifically,
economically, and socially—in biomedical research. Advances in informatics and …