Extracellular vesicles (EVs) are nano-sized, membranous structures secreted into the
extracellular space. They exhibit diverse sizes, contents, and surface markers and are …

Cellular communication can be mediated by the exchange of biological information, mainly
in the form of proteins and RNAs. This can occur when extracellular vesicles, such as …

Cancer cells continuously rewire their metabolism to fulfill their need for rapid growth and
survival while subject to changes in environmental cues. Thus, a vital component of a cancer …

Exosomes are secreted nanovesicles with potent signalling activity that are initially formed
as intraluminal vesicles (ILVs) in late Rab7‐positive multivesicular endosomes, and also in …

Exosomes are nano-vesicles (NVs) secreted by cells and take part in cell-cell
communications. Lately, these exosomes were proved to have dual faces in cancer …

Prostate cancer (PCa) is the most common solid tumor in men. While patients with local PCa
have better prognostic survival, patients with metastatic PCa have relatively high mortality …

Tumor cells express a high quantity of exosomes packaged with unique cargos under
hypoxia, an important characteristic feature in solid tumors. These hypoxic tumor-derived …

Patients with advanced prostate cancer (PCa) frequently develop skeletal metastases that
are associated with fractures, disability, and increased mortality. Within the bone metastatic …

Simple Summary Recently, within the research community, exosomes, transporters of
bioactive molecules involved in many signalling pathways and cell-to-cell communication …

Although integrin alpha 2 subunit (ITGA2) mediates cancer progression and metastasis, its
transfer by exosomes has not been investigated in prostate cancer (PCa). We aimed to …