Addiction is driven by excessive goal-directed drug choice under negative affect: translational critique of habit and compulsion theory

L Hogarth - Neuropsychopharmacology, 2020 - nature.com
Drug addiction may be a goal-directed choice driven by excessive drug value in negative
affective states, a habit driven by strong stimulus− response associations, or a compulsion …

Rodent models for compulsive alcohol intake

FW Hopf, HMB Lesscher - Alcohol, 2014 - Elsevier
Continued seeking and drinking of alcohol despite adverse legal, health, economic, and
societal consequences is a central hallmark of human alcohol use disorders. This …

Habit, choice, and addiction

Y Vandaele, SH Ahmed - Neuropsychopharmacology, 2021 - nature.com
Addiction was suggested to emerge from the progressive dominance of habits over goal-
directed behaviors. However, it is generally assumed that habits do not persist in choice …

Memory systems and the addicted brain

J Goodman, MG Packard - Frontiers in psychiatry, 2016 - frontiersin.org
The view that anatomically distinct memory systems differentially contribute to the
development of drug addiction and relapse has received extensive support. The present …

Bad habits–good goals? Meta-analysis and translation of the habit construct to alcoholism

F Giannone, C Ebrahimi, T Endrass… - Translational …, 2024 - nature.com
Excessive alcohol consumption remains a global public health crisis, with millions suffering
from alcohol use disorder (AUD, or simply “alcoholism”), leading to significantly reduced life …

Habitual alcohol seeking: neural bases and possible relations to alcohol use disorders

LH Corbit, PH Janak - Alcoholism: Clinical and Experimental …, 2016 - Wiley Online Library
Loss of flexible control over alcohol use may contribute to the development of alcohol use
disorders. An increased contribution of response habits to alcohol‐related behaviors may …

Defining the place of habit in substance use disorders

Y Vandaele, PH Janak - Progress in Neuro-Psychopharmacology and …, 2018 - Elsevier
It has long been suggested that alcohol or substance use disorders could emerge from the
progressive development and dominance of drug habits. Like habits, drug-related behaviors …

Intact goal‐directed control in treatment‐seeking drug users indexed by outcome‐devaluation and Pavlovian to instrumental transfer: critique of habit theory

L Hogarth, C Lam‐Cassettari, H Pacitti… - European Journal of …, 2019 - Wiley Online Library
Animal studies have demonstrated that chronic exposure to drugs of abuse impairs goal‐
directed control over action selection indexed by the outcome‐devaluation and specific …

Acute alcohol and cognition: Remembering what it causes us to forget

CE Van Skike, C Goodlett, DB Matthews - Alcohol, 2019 - Elsevier
Addiction has been conceptualized as a specific form of memory that appropriates typically
adaptive neural mechanisms of learning to produce the progressive spiral of drug-seeking …

Corticostriatal circuitry and habitual ethanol seeking

JM Barker, LH Corbit, DL Robinson, CM Gremel… - Alcohol, 2015 - Elsevier
The development of alcohol-use disorders is thought to involve a transition from casual
alcohol use to uncontrolled alcohol-seeking behavior. This review will highlight evidence …