Oligodendrocytes are the myelinating cells of the central nervous system that constitute
about 5 to 10% of the total glial population. These cells are responsible for myelin sheath …

Oligodendrocytes, the myelin‐forming cells of the central nervous system, are in culture
characterized by an elaborate process network, terminating in flat membranous sheets that …

New neurons and oligodendrocytes are continuously produced in the subventricular zone
(SVZ) of adult mammalian brains. Under normal conditions, the SVZ primary precursors …

Microtubule‐associated protein Tau is primarily expressed in axons of neurons, but also in
Olig2‐positive oligodendrocytes in adult rodent and monkey brains. In this study, we sought …

TPPP/p25, a recently identified tubulin polymerization‐promoting protein (TPPP), is
expressed mainly in myelinating oligodendrocytes of the CNS. Here, we show that …

Myelin, formed by oligodendrocytes (OLs) in the CNS, is critical for axonal functions, and its
damage leads to debilitating neurological disorders such as multiple sclerosis …

Oligodendrocytes form an insulating multilamellar structure of compact myelin around
axons, thereby allowing rapid propagation of action potentials. Despite the considerable …

Introduction Spinal cord injury (SCI) can cause paralysis, for which effective therapeutic
strategies have not been developed yet. The only accepted strategy for patients is …

Mutations in the extracellular signal-regulated kinase (ERK) pathway, particularly in the
mitogen-activated protein kinase/ERK kinase (MEK) activator B-Raf, are associated with …

Previous work from our laboratory demonstrated that the mammalian target of rapamycin
(mTOR) is active during and required for oligodendrocyte progenitor cell (OPC) …