Introduction: Focal adhesion kinase (FAK) is a promising target for the treatment of solid
tumors because its expression has been linked to tumor progression, invasion, and drug …

Cells express various cell surface adhesion molecules (receptors) that not only
mechanically serve as contacting sites between the cell and extracellular matrix (ECM) or …

RNA-seq is a promising technology to re-sequence protein coding genes for the
identification of single nucleotide variants (SNV), while simultaneously obtaining information …

Small‐cell lung cancer (SCLC) is a subtype of lung cancer with poor prognosis. To identify
accurate predictive biomarkers and effective therapeutic modalities, we focus on a long …

Abstract miR-187-3p, a novel cancer-related microRNA, was previously reported to play
promoting or suppressive roles in different malignancies. However, the expression level …

Purpose: We aimed to investigate the effects of adiponectin on liver cancer growth and
metastasis and explore the underlying mechanisms. Experimental Design: An orthotopic …

Background Cuproptosis is a novel form of programmed cell death that differs from other
types such as pyroptosis, ferroptosis, and autophagy. It is a promising new target for cancer …

Tumor metastasis is the main cause of cancer-related deaths of patients. Breast cancer is
highly malignant with considerable metastatic potential, which urges the necessity for …

Abstract Glypican 3 (GPC3) is a valuable diagnostic marker and a potential therapeutic
target in hepatocellular carcinoma (HCC). To evaluate the efficacy of targeting GPC3 at the …

Background Cannabinoids bind to cannabinoid receptors CB1 and CB2 and have been
reported to possess anti-tumorigenic activity in various cancers. However, the mechanisms …