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The changing metabolic landscape of bile acids–keys to metabolism and immune regulation
Bile acids regulate nutrient absorption and mitochondrial function, they establish and
maintain gut microbial community composition and mediate inflammation, and they serve as …
maintain gut microbial community composition and mediate inflammation, and they serve as …
Crosstalk between gut microbiota and host immunity: impact on inflammation and immunotherapy
Gut microbes and their metabolites are actively involved in the development and regulation
of host immunity, which can influence disease susceptibility. Herein, we review the most …
of host immunity, which can influence disease susceptibility. Herein, we review the most …
Nutritional regulation of microbiota-derived metabolites: Implications for immunity and inflammation
Nutrition profoundly shapes immunity and inflammation across the lifespan of mammals,
from pre-and post-natal periods to later life. Emerging insights into diet-microbiota …
from pre-and post-natal periods to later life. Emerging insights into diet-microbiota …
Immunomodulatory effects of inulin and its intestinal metabolites
W Sheng, G Ji, L Zhang - Frontiers in immunology, 2023 - frontiersin.org
“Dietary fiber”(DF) refers to a type of carbohydrate that cannot be digested fully. DF is not an
essential nutrient, but it plays an important part in enhancing digestive capacity and …
essential nutrient, but it plays an important part in enhancing digestive capacity and …
The microbial metabolite agmatine acts as an FXR agonist to promote polycystic ovary syndrome in female mice
C Yun, S Yan, B Liao, Y Ding, X Qi, M Zhao… - Nature …, 2024 - nature.com
Polycystic ovary syndrome (PCOS), an endocrine disorder afflicting 6–20% of women of
reproductive age globally, has been linked to alterations in the gut microbiome. We …
reproductive age globally, has been linked to alterations in the gut microbiome. We …
How bile acids and the microbiota interact to shape host immunity
Bile acids are increasingly appearing in the spotlight owing to their novel impacts on various
host processes. Similarly, there is growing attention on members of the microbiota that are …
host processes. Similarly, there is growing attention on members of the microbiota that are …
A major mechanism for immunomodulation: Dietary fibres and acid metabolites
Diet and the gut microbiota have a profound influence on physiology and health, however,
mechanisms are still emerging. Here we outline several pathways that gut microbiota …
mechanisms are still emerging. Here we outline several pathways that gut microbiota …
[HTML][HTML] Bile acids, intestinal barrier dysfunction, and related diseases
The intestinal barrier is a precisely regulated semi-permeable physiological structure that
absorbs nutrients and protects the internal environment from infiltration of pathological …
absorbs nutrients and protects the internal environment from infiltration of pathological …
Inulin diet uncovers complex diet-microbiota-immune cell interactions remodeling the gut epithelium
Background The continuous proliferation of intestinal stem cells followed by their tightly
regulated differentiation to epithelial cells is essential for the maintenance of the gut …
regulated differentiation to epithelial cells is essential for the maintenance of the gut …
The role of diet and nutrition in allergic diseases
P Zhang - Nutrients, 2023 - mdpi.com
Allergic diseases are a set of chronic inflammatory disorders of lung, skin, and nose
epithelium characterized by aberrant IgE and Th2 cytokine-mediated immune responses to …
epithelium characterized by aberrant IgE and Th2 cytokine-mediated immune responses to …