Gut microbiota‐derived metabolites are key hubs connecting the gut microbiome and cancer
progression, primarily by remodeling the tumor microenvironment and regulating key …

Biopsy, including tissue and liquid biopsy, offers comprehensive and real-time physiological
and pathological information for disease detection, diagnosis, and monitoring. Fluorescent …

Disease relapse driven by acquired drug resistance limits the effectiveness of most systemic
anti-cancer agents. Targeting persistent cancer cells in residual disease before relapse has …

Lung cancer maintains a high morbidity and mortality rate globally despite significant
advancements in detection and therapy in the era of precision medicine. Excisional biopsy …

Liquid biopsies have emerged as a minimally invasive cancer detection and monitoring
method, which could identify cancer-related alterations in nucleosome or histone levels and …

Nucleosomes play a crucial role in regulating gene expression through their composition
and post-translational modifications. When cells die, intracellular endonucleases are …

Abstract Laser Wakefield Acceleration (LWFA) has emerged as a groundbreaking approach
for generating ultra-high energy electron beams over short distances, revolutionizing the …

Cancer cells are highly heterogeneous at the transcriptional level and epigenetic state.
Methods to study epigenetic heterogeneity are limited in throughput and information …

Immune and inflammatory processes occurring within tissues are often undetectable by
blood cell counts, standard circulating biomarkers, or imaging, representing an unmet …

Genomes are self-organized and self-maintained as long, complex macromolecules of
chromatin. The inherent heterogeneity, stochasticity, phase separation, and chromatin …