[HTML][HTML] A review on metal complexes and its anti-cancer activities: Recent updates from in vivo studies

S Adhikari, P Nath, A Das, A Datta, N Baildya… - Biomedicine & …, 2024 - Elsevier
Research into cancer therapeutics has uncovered various potential medications based on
metal-containing scaffolds after the discovery and clinical applications of cisplatin as an anti …

A comprehensive overview of β-carbolines and its derivatives as anticancer agents

B Luo, X Song - European Journal of Medicinal Chemistry, 2021 - Elsevier
Abstract β-Carboline alkaloids are a family of natural and synthetic products with structural
diversity and outstanding antitumor activities. This review summarizes research …

Anticancer potential of Β‐Carboline alkaloids: an updated mechanistic overview

PP Tshikhudo, T Mabhaudhi… - Chemistry & …, 2024 - Wiley Online Library
Abstract his comprehensive review is designed to evaluate the anticancer properties of β‐
carbolines derived from medicinal plants, with the ultimate goal of assessing their suitability …

Novel palladium (II) and Zinc (II) Schiff base complexes: synthesis, biophysical studies, and anticancer activity investigation

HM Fahmy, AM Mosleh, AA El-Sayed… - Journal of Trace Elements …, 2023 - Elsevier
Background Schiff base metal complexes are considered promising chemotherapeutic
agents due to their potential application in cancer therapy. Methods The current work sought …

New ternary Fe (III)-8-hydroxyquinoline–reduced Schiff base complexes as selective anticancer drug candidates

V Ferretti, CP Matos, C Canelas, JC Pessoa… - Journal of Inorganic …, 2022 - Elsevier
Due to the growing prevalence of cancer diseases, new therapeutic options are urgently
needed, and drugs based on metal ions other than platinum are alternatives with exciting …

[HTML][HTML] Comparative efficacy of ternary Cu (II) complex and Zn (II)-complex in amelioration of carbon tetrachloride-induced hepatotoxicity in vivo

I Hassan, RA Khan, J Al-Tamimi, H Ebaid… - Journal of King Saud …, 2023 - Elsevier
Abstract Cu (II) and Zn (II) are two of the most favored metals in synthesis chemistry,
encompassing their therapeutic potentials. The present study aims to evaluate the …

Piano-stool type (η6-p-cymene) ruthenium (II) thiazole-derived motifs complexes: Synthesis, crystal structures, DFT studies, molecular docking and in-vitro binding …

RA Khan, SS Alterary, II BinSharfan, H Alsaeedi… - Inorganica Chimica …, 2022 - Elsevier
Herein, two new p-cymene ruthenium (II) complexes [(η 6-p-cymene) Ru (L 1-OH) Cl] 1 and
[(η 6-p-cymene) Ru (L 2-OH) Cl] 2 of thiazolyl-derived ligands ie,(E)-2-(((5-methylthiazol-2 …

Study of novel bidentate heterocyclic amine-based metal complexes and their biological activities: cytotoxicity and antimicrobial activity evaluation

HM Fahmy, FM Abdel-Rahman, AA El-Sayed… - BMC chemistry, 2023 - Springer
Metallic antitumor drugs with heterocyclic ligands, such as novel AMI (amino methyl
imidazole) complexes [Pd (AMI) Cl2](1),[Cu (AMI) L1](2), and [Cu (AMI) L2· 2H2O](3) where …

Sulfur-containing β-Carbolines: Synthesis and Biological Study

VR Akhmetova, DV Leont'ev, NS Akhmadiev - β-Carbolines - taylorfrancis.com
This chapter summarizes the achievements of the past two decades on the synthesis of S-
containing derivatives of β-carboline (9H-pyrido [3, 4-b] indole), which is the basic scaffold …