Conditioning of the immune system by the microbiome

DB Graham, RJ Xavier - Trends in Immunology, 2023 - cell.com
The human intestinal microbiome has coevolved with its host to establish a stable
homeostatic relationship with hallmark features of mutualistic symbioses, yet the mechanistic …

Immunogenicity of bacteriophages

K Champagne-Jorgensen, T Luong, T Darby… - Trends in …, 2023 - cell.com
Hundreds of trillions of diverse bacteriophages (phages) peacefully thrive within and on the
human body. However, whether and how phages influence their mammalian hosts is poorly …

[HTML][HTML] Fermented foods: Harnessing their potential to modulate the microbiota-gut-brain axis for mental health

R Balasubramanian, E Schneider, E Gunnigle… - Neuroscience & …, 2024 - Elsevier
Over the past two decades, whole food supplementation strategies have been leveraged to
target mental health. In addition, there has been increasing attention on the ability of gut …

The roles of gut microbiota and its metabolites in diabetic nephropathy

H Zhao, CE Yang, T Liu, MX Zhang, Y Niu… - Frontiers in …, 2023 - frontiersin.org
Diabetic nephropathy (DN) is a severe microvascular complication of diabetes, which
increases the risk of renal failure and causes a high global disease burden. Due to the lack …

Pathophysiology of inflammatory bowel disease: innate immune system

A Saez, B Herrero-Fernandez, R Gomez-Bris… - International journal of …, 2023 - mdpi.com
Inflammatory bowel disease (IBD), comprising Crohn's disease (CD) and ulcerative colitis
(UC), is a heterogeneous state of chronic intestinal inflammation with no exact known cause …

Microbiome influencers of checkpoint blockade–associated toxicity

Y Wang, RR Jenq, JA Wargo… - Journal of Experimental …, 2023 - rupress.org
Immunotherapy has greatly improved cancer outcomes, yet variability in response and off-
target tissue damage can occur with these treatments, including immune checkpoint …

Commensal lifestyle regulated by a negative feedback loop between Arabidopsis ROS and the bacterial T2SS

F Entila, X Han, A Mine, P Schulze-Lefert… - Nature …, 2024 - nature.com
Despite the plant health-promoting effects of plant microbiota, these assemblages also
comprise potentially detrimental microbes. How plant immunity controls its microbiota to …

Microbial sensing in the intestine

T Wan, Y Wang, K He, S Zhu - Protein & Cell, 2023 - academic.oup.com
The gut microbiota plays a key role in host health and disease, particularly through their
interactions with the immune system. Intestinal homeostasis is dependent on the symbiotic …

Map** the T cell repertoire to a complex gut bacterial community

K Nagashima, A Zhao, K Atabakhsh, M Bae, JE Blum… - Nature, 2023 - nature.com
Certain bacterial strains from the microbiome induce a potent, antigen-specific T cell
response,,,–. However, the specificity of microbiome-induced T cells has not been explored …

The next generation fecal microbiota transplantation: to transplant bacteria or virome

Y Yu, W Wang, F Zhang - Advanced Science, 2023 - Wiley Online Library
Fecal microbiota transplantation (FMT) has emerged as a promising therapeutic approach
for dysbiosis‐related diseases. However, the clinical practice of crude fecal transplants …