The inositol trisphosphate/calcium signaling pathway in health and disease
MJ Berridge - Physiological reviews, 2016 - journals.physiology.org
Many cellular functions are regulated by calcium (Ca2+) signals that are generated by
different signaling pathways. One of these is the inositol 1, 4, 5-trisphosphate/calcium …
different signaling pathways. One of these is the inositol 1, 4, 5-trisphosphate/calcium …
The control of diastolic calcium in the heart: basic mechanisms and functional implications
Normal cardiac function requires that intracellular Ca2+ concentration be reduced to low
levels in diastole so that the ventricle can relax and refill with blood. Heart failure is often …
levels in diastole so that the ventricle can relax and refill with blood. Heart failure is often …
The role of the dystrophin glycoprotein complex in muscle cell mechanotransduction
Dystrophin is the central protein of the dystrophin-glycoprotein complex (DGC) in skeletal
and heart muscle cells. Dystrophin connects the actin cytoskeleton to the extracellular matrix …
and heart muscle cells. Dystrophin connects the actin cytoskeleton to the extracellular matrix …
Ion channels of the sarcolemma and intracellular organelles in Duchenne muscular dystrophy: a role in the dysregulation of ion homeostasis and a possible target for …
Duchenne muscular dystrophy (DMD) is caused by the absence of the dystrophin protein
and a properly functioning dystrophin-associated protein complex (DAPC) in muscle cells …
and a properly functioning dystrophin-associated protein complex (DAPC) in muscle cells …
Disrupted calcium homeostasis in duchenne muscular dystrophy: A common mechanism behind diverse consequences
B Zabłocka, DC Górecki, K Zabłocki - International Journal of Molecular …, 2021 - mdpi.com
Duchenne muscular dystrophy (DMD) leads to disability and death in young men. This
disease is caused by mutations in the DMD gene encoding diverse isoforms of dystrophin …
disease is caused by mutations in the DMD gene encoding diverse isoforms of dystrophin …
[HTML][HTML] Cardiomyopathy in Duchenne Muscular Dystrophy and the Potential for Mitochondrial Therapeutics to Improve Treatment Response
S Gandhi, HL Sweeney, CC Hart, R Han, CGR Perry - Cells, 2024 - mdpi.com
Duchenne muscular dystrophy (DMD) is a progressive neuromuscular disease caused by
mutations to the dystrophin gene, resulting in deficiency of dystrophin protein, loss of …
mutations to the dystrophin gene, resulting in deficiency of dystrophin protein, loss of …
Current pharmacological strategies for Duchenne muscular dystrophy
S Yao, Z Chen, Y Yu, N Zhang, H Jiang… - Frontiers in Cell and …, 2021 - frontiersin.org
Duchenne muscular dystrophy (DMD) is a lethal, X-linked neuromuscular disorder caused
by the absence of dystrophin protein, which is essential for muscle fiber integrity. Loss of …
by the absence of dystrophin protein, which is essential for muscle fiber integrity. Loss of …
Quantum blue reduces the severity of woody breast myopathy via modulation of oxygen homeostasis-related genes in broiler chickens
The incidence of woody breast (WB) is increasing on a global scale representing a
significant welfare problem and economic burden to the poultry industry and for which there …
significant welfare problem and economic burden to the poultry industry and for which there …
The endothelium as a therapeutic target in diabetes: a narrative review and perspective
Diabetes has reached worldwide epidemic proportions, and threatens to be a significant
economic burden to both patients and healthcare systems, and an important driver of …
economic burden to both patients and healthcare systems, and an important driver of …
Effects of naringin on cardiomyocytes from a rodent model of type 2 diabetes
Diabetic cardiomyopathy (DCM) is a primary disease in diabetic patients characterized by
diastolic dysfunction leading to heart failure and death. Unfortunately, even tight glycemic …
diastolic dysfunction leading to heart failure and death. Unfortunately, even tight glycemic …