SARS-CoV-2 ORF6 disrupts innate immune signalling by inhibiting cellular mRNA export
SARS-CoV-2 is a betacoronavirus and the etiological agent of COVID-19, a devastating
infectious disease. Due to its far-reaching effect on human health, there is an urgent and …
infectious disease. Due to its far-reaching effect on human health, there is an urgent and …
Nanoscopic elucidation of spontaneous self-assembly of Severe Acute Respiratory Syndrome Coronavirus 2 (SARS-CoV-2) open reading frame 6 (ORF6) protein
Open reading frame 6 (ORF6), the accessory protein of severe acute respiratory syndrome
coronavirus 2 (SARS-CoV-2) that suppresses host type-I interferon signaling, possesses …
coronavirus 2 (SARS-CoV-2) that suppresses host type-I interferon signaling, possesses …
AThe M-motif: a potential new class of non-conventional NLS in TAZ/YAP and other cellular and viral proteins that inhibits classic protein import
Multiple mechanisms were proposed to mediate the nuclear import of TAZ/YAP,
transcriptional co-activators regulating organ growth and regeneration. Our earlier …
transcriptional co-activators regulating organ growth and regeneration. Our earlier …
Interferon-γ as a Potential Inhibitor of SARS-CoV-2 ORF6 Accessory Protein
The ORF6 protein of the SARS-CoV-2 virus plays a crucial role in blocking the innate
immune response of the infected cells by inhibiting interferon pathways. Additionally, it binds …
immune response of the infected cells by inhibiting interferon pathways. Additionally, it binds …
SARS-CoV-2 Orf6 requires the Nup98/Rae1 complex to inhibit host nuclear transport
ND Love - 2023 - era.library.ualberta.ca
The nucleus is a hallmark organelle of eukaryotes. It separates the genetic material from the
rest of the cytoplasm using a selectively permeable double phospholipid bilayer called the …
rest of the cytoplasm using a selectively permeable double phospholipid bilayer called the …