Conspectus Naturally occurring glycans and glycoconjugates have extremely diverse
structures and biological functions. Syntheses of these molecules and their artificial mimics …

Covering: 2000 to 2020 Triptolide is a bioactive diterpene triepoxide isolated from
Tripterygium wilfordii Hook F, a traditional Chinese medicinal plant whose extracts have …

Introduction: Throughout history, natural products (NPs) have provided a rich source of
compounds that have wide applications in the fields of medicine, health sciences, pharmacy …

Triple-negative breast cancer (TNBC) lacks three important receptors, ER, PR, and HER2. It
is more aggressive and more likely to relapse after treatment, thus has been identified as …

Glucose‐responsive delivery of insulin mimicking the function of pancreatic β‐cells to
achieve meticulous control of blood glucose (BG) would revolutionize diabetes care. Here …

One of the characteristics of cancer cells important for tumorigenesis is their metabolic
plasticity. Indeed, in various stress conditions, cancer cells can reshape their metabolic …

In the past decades, triptolide has attracted considerable interests in the organic and
medicinal chemistry society owing to its intriguing structure features and promising multiple …

Pancreatic ductal adenocarcinoma (PDAC) is a devastating disease exhibiting the poorest
prognosis among solid tumors. The efficacy of conventional therapies has been hindered …

Oligosaccharides are the ubiquitous molecules of life. In order to translate human
bioglycosylation into clinical applications, homogeneous samples of oligosaccharides and …

Glycosylated platinum (IV) complexes were synthesized as substrates for GLUTs and OCTs
for the first time, and the cytotoxicity and detailed mechanism were determined in vitro and in …