Application of patient-specific computational fluid dynamics in coronary and intra-cardiac flow simulations: Challenges and opportunities

L Zhong, JM Zhang, B Su, RS Tan, JC Allen… - Frontiers in …, 2018 - frontiersin.org
The emergence of new cardiac diagnostics and therapeutics of the heart has given rise to
the challenging field of virtual design and testing of technologies in a patient-specific …

Perspective on CFD studies of coronary artery disease lesions and hemodynamics: a review

JM Zhang, L Zhong, B Su, M Wan… - … journal for numerical …, 2014 - Wiley Online Library
Coronary artery disease (CAD) is the most common cardiovascular disease. Early diagnosis
of CAD's physiological significance is of utmost importance for guiding individualized risk …

The fluid-structure interaction during blood flow in a flexible stenotic thoracic aorta: Numerical study

A Issakhov, A Sabyrkulova, A Abylkassymova - Computers & Mathematics …, 2024 - Elsevier
A detailed study of the effect of coarctation on the blood flow of the thoracic aorta was carried
out by modeling the interaction between blood and the aortic wall. Fluid-structure interaction …

Numerical modeling of the fluid-structure interaction during blood flow in a flexible stenotic aorta

A Issakhov, A Sabyrkulova, A Abylkassymova - … Communications in Heat …, 2024 - Elsevier
The aim of this study is to understand the relationship between blood flow and vascular
mechanics in stenotic and healthy arteries and use this understanding to improve the …

Computational fluid dynamic simulations of image-based stented coronary bifurcation models

C Chiastra, S Morlacchi, D Gallo… - Journal of The …, 2013 - royalsocietypublishing.org
One of the relevant phenomenon associated with in-stent restenosis in coronary arteries is
an altered haemodynamics in the stented region. Computational fluid dynamics (CFD) offers …

The atheroprotective nature of helical flow in coronary arteries

G De Nisco, AM Kok, C Chiastra, D Gallo… - Annals of biomedical …, 2019 - Springer
Arterial hemodynamics is markedly characterized by the presence of helical flow patterns.
Previous observations suggest that arterial helical blood flow is of physiological significance …

Effect of wall elasticity on hemodynamics and wall shear stress in patient-specific simulations in the coronary arteries

P Eslami, J Tran, Z **, J Karady… - Journal of …, 2020 - asmedigitalcollection.asme.org
Wall shear stress (WSS) has been shown to be associated with myocardial infarction (MI)
and progression of atherosclerosis. Wall elasticity is an important feature of hemodynamic …

[HTML][HTML] On the nonlinear relationship between wall shear stress topology and multi-directionality in coronary atherosclerosis

HJ Carpenter, MH Ghayesh, AC Zander… - Computer Methods and …, 2023 - Elsevier
Abstract Background and Objective In this paper we investigate twelve multi-
directional/topological wall shear stress (WSS) derived metrics and their relationships with …

Integrating computational and biological hemodynamic approaches to improve modeling of atherosclerotic arteries

TNAM Vuong, M Bartolf‐Kopp, K Andelovic… - Advanced …, 2024 - Wiley Online Library
Atherosclerosis is the primary cause of cardiovascular disease, resulting in mortality,
elevated healthcare costs, diminished productivity, and reduced quality of life for individuals …

[HTML][HTML] Computational analysis of the coronary artery hemodynamics with different anatomical variations

MF Rabbi, FS Laboni, MT Arafat - Informatics in Medicine Unlocked, 2020 - Elsevier
Hemodynamic parameters have been identified as a significant determinant in the
development and progression of plaque, which leads to coronary artery disease (CAD). This …