Exposure to pro-inflammatory cytokines, chemokines, mitochondrial contents, and bacterial
and viral products induces neutrophils to transition from a basal state into a primed one …

As current research illuminates the dynamic interplay between the innate and acquired
immune responses, the interaction and communication between these two arms has yet to …

Mature circulating polymorphonuclear cells (PMN) have the shortest half-life among
leukocytes and undergo rapid programmed cell death in vitro. In this study, we have …

Recombinant tumor necrosis factor alpha (rTNF alpha) and beta (rTNF beta) did not trigger
H2O2 release from PMN in suspension. However, when PMN were plated on polystyrene …

Publisher Summary This chapter focuses on studies of the murine and human leukocyte
FcγR and FCɛR I, with particular reference to the structural characterization of these …

Chimeric antibodies were constructed in which the murine variable region of anti-colorectal
cancer monoclonal antibody CO17-1A was joined with human gamma 1, gamma 2, gamma …

Background Interleukin (IL)–32 is a newly described proinflammatory cytokine that seems
likely to play a role in inflammation and host defense. Little is known about the regulation of …

Purpose The unique immunoglobulin idiotype (Id) expressed by each B-cell lymphoma is a
target for immunotherapy. Vaccination with Id induces humoral and/or cellular anti-Id …

Abstract The cytokine interleukin 6 (IL-6) has been shown to have multiple biological
activities against many cellular targets. The present studies were designed to determine …

In this study, we analyzed the expression of genes encoding for components of the
phagocyte superoxide anion-generating system in human phagocytes treated with interferon …