Mechanisms of mechanical overload-induced skeletal muscle hypertrophy: current understanding and future directions

MD Roberts, JJ McCarthy… - Physiological …, 2023 - journals.physiology.org
Mechanisms underlying mechanical overload-induced skeletal muscle hypertrophy have
been extensively researched since the landmark report by Morpurgo (1897) of “work …

The effects of resistance training to near failure on strength, hypertrophy, and motor unit adaptations in previously trained adults

BA Ruple, DL Plotkin, MA Smith, JS Godwin… - Physiological …, 2023 - Wiley Online Library
Limited research exists examining how resistance training to failure affects applied
outcomes and single motor unit characteristics in previously trained individuals. Herein …

Changes in vastus lateralis fibre cross‐sectional area, pennation angle and fascicle length do not predict changes in muscle cross‐sectional area

BA Ruple, PHC Mesquita, JS Godwin… - Experimental …, 2022 - Wiley Online Library
New Findings What is the central question of this study? Do changes in myofibre cross‐
sectional area, pennation angle and fascicle length predict vastus lateralis whole‐muscle …

Can muscle typology explain the inter‐individual variability in resistance training adaptations?

K Van Vossel, J Hardeel… - The Journal of …, 2023 - Wiley Online Library
Considerable inter‐individual heterogeneity exists in the muscular adaptations to resistance
training. It has been proposed that fast‐twitch fibres are more sensitive to hypertrophic …

Myofiber hypertrophy adaptations following 6 weeks of low-load resistance training with blood flow restriction in untrained males and females

TM Reece, JS Godwin, MJ Strube… - Journal of Applied …, 2023 - journals.physiology.org
The effects of low-load resistance training with blood flow restriction (BFR) on hypertrophy of
type I/II myofibers remains unclear, especially in females. The purpose of the present study …

Critical evaluation of commonly used methods to determine the concordance between sonography and magnetic resonance imaging: a comparative study

K Warneke, M Keiner, LH Lohmann, A Brinkmann… - Frontiers in …, 2022 - frontiersin.org
Introduction An increasing number of studies investigate the influence of training
interventions on muscle thickness (MT) by using ultrasonography. Ultrasonography is stated …

Resistance training diminishes mitochondrial adaptations to subsequent endurance training in healthy untrained men

PHC Mesquita, JS Godwin, BA Ruple… - The Journal of …, 2023 - Wiley Online Library
We investigated the effects of performing a period of resistance training (RT) on the
performance and molecular adaptations to a subsequent period of endurance training (ET) …

Limited effect of over-the-counter doses of ibuprofen on mechanisms regulating muscle hypertrophy during resistance training in young adults

M Lilja, M Moberg, W Apró… - Journal of Applied …, 2023 - journals.physiology.org
We have previously shown that maximal over-the-counter doses of ibuprofen, compared
with low doses of acetylsalicylic acid, reduce muscle hypertrophy in young individuals after 8 …

Skeletal muscle adaptations to high‐intensity, low‐volume concurrent resistance and interval training in recreationally active men and women

AJ Sterczala, N Rodriguez‐Ortiz, ED Feigel… - Physiological …, 2024 - Wiley Online Library
This study compared the structural and cellular skeletal muscle factors underpinning
adaptations in maximal strength, power, aerobic capacity, and lean body mass to a 12‐week …

Relative rDNA copy number is not associated with resistance training-induced skeletal muscle hypertrophy and does not affect myotube anabolism in vitro

JS Godwin, JM Michel, AT Ludlow… - American Journal …, 2024 - journals.physiology.org
Ribosomal DNA (rDNA) copies exist across multiple chromosomes, and interindividual
variation in copy number is speculated to influence the hypertrophic response to resistance …