Food and nutraceutical functions of sesame oil: An underutilized crop for nutritional and health benefits

S Langyan, P Yadava, S Sharma, NC Gupta, R Bansal… - Food chemistry, 2022 - Elsevier
Sesame is the oldest oilseed crop known to humanity, though it contributes a small share in
the global vegetable oil production. Sesame oil contains nutrients, including lignans …

An update on the rotenone models of Parkinson's disease: their ability to reproduce the features of clinical disease and model gene–environment interactions

ME Johnson, L Bobrovskaya - Neurotoxicology, 2015 - Elsevier
Parkinson's disease (PD) is the second most common neurodegenerative disorder that is
characterized by two major neuropathological hallmarks: the degeneration of dopaminergic …

Acetylcholinesterase inhibitors in the treatment of neurodegenerative diseases and the role of acetylcholinesterase in their pathogenesis

ŁJ Walczak-Nowicka, M Herbet - International journal of molecular …, 2021 - mdpi.com
Acetylcholinesterase (AChE) plays an important role in the pathogenesis of
neurodegenerative diseases by influencing the inflammatory response, apoptosis, oxidative …

The Nrf2/HO‐1 Axis as targets for flavanones: Neuroprotection by pinocembrin, naringenin, and Eriodictyol

S Habtemariam - Oxidative medicine and cellular longevity, 2019 - Wiley Online Library
Flavanones are a group of flavonoids that derive from their immediate chalcone precursors
through the action of chalcone isomerase enzymes. The Aromatic A and B rings, C4‐keto …

Multi-therapeutic potential of naringenin (4′, 5, 7-trihydroxyflavonone): experimental evidence and mechanisms

A Arafah, MU Rehman, TM Mir, AF Wali, R Ali… - Plants, 2020 - mdpi.com
Extensive research has been carried out during the last few decades, providing a detailed
account of thousands of discovered phytochemicals and their biological activities that have …

Polyphenols in Parkinson's disease: a systematic review of in vivo studies

M Kujawska, J Jodynis-Liebert - Nutrients, 2018 - mdpi.com
Parkinson's disease (PD) is the second most common neurodegenerative disorder.
However, therapeutic options treating only its symptoms are very disappointing. Therefore …

Naringenin: A prospective therapeutic agent for Alzheimer's and Parkinson's disease

A Goyal, A Verma, N Dubey, J Raghav… - Journal of Food …, 2022 - Wiley Online Library
Neurodegenerative disorders (NDs) are a cluster of progressive, severe, and disabling
disorders that affect millions of people worldwide and are on the surge. These disorders are …

On the neuroprotective effects of naringenin: pharmacological targets, signaling pathways, molecular mechanisms, and clinical perspective

Z Nouri, S Fakhri, FF El-Senduny, N Sanadgol… - Biomolecules, 2019 - mdpi.com
As a group of progressive, chronic, and disabling disorders, neurodegenerative diseases
(NDs) affect millions of people worldwide, and are on the rise. NDs are known as the …

[HTML][HTML] Harnessing role of sesamol and its nanoformulations against neurodegenerative diseases

N Singh, S Vishwas, A Kaur, H Kaur, V Kakoty… - Biomedicine & …, 2023 - Elsevier
Sesamol is a lignan of sesame seeds and a natural phenolic molecule that has emerged as
a useful medical agent. Sesamol is a non-toxic phytoconstituent, which exerts certain …

[HTML][HTML] Sesamol alleviates manganese-induced neuroinflammation and cognitive impairment via regulating the microglial cGAS-STING/NF-κB pathway

J Wu, H Chen, T Guo, M Li, C Yang, M Aschner… - Environmental …, 2023 - Elsevier
Toxic effects of excessive manganese (Mn) from occupational or environmental exposure
cause harm to human health. Excessive Mn exposure is intimately associated with …