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Progressive multiple sclerosis: prospects for disease therapy, repair, and restoration of function
Multiple sclerosis is a major cause of neurological disability, which accrues predominantly
during progressive forms of the disease. Although development of multifocal inflammatory …
during progressive forms of the disease. Although development of multifocal inflammatory …
Brain MRI atrophy quantification in MS: from methods to clinical application
Patients with the main clinical phenotypes of multiple sclerosis (MS) manifest varying
degrees of brain atrophy beyond that of normal aging. Assessment of atrophy helps to …
degrees of brain atrophy beyond that of normal aging. Assessment of atrophy helps to …
Imaging of the optic nerve: technological advances and future prospects
Over the past decade, ocular imaging strategies have greatly advanced the diagnosis and
follow-up of patients with optic neuropathies. Developments in optic nerve imaging have …
follow-up of patients with optic neuropathies. Developments in optic nerve imaging have …
Brain atrophy in multiple sclerosis: mechanisms, clinical relevance and treatment options
Multiple sclerosis (MS) is an immune-mediated disease of the central nervous system
characterized by focal or diffuse inflammation, demyelination, axonal loss and …
characterized by focal or diffuse inflammation, demyelination, axonal loss and …
Retinal layer segmentation in multiple sclerosis: a systematic review and meta-analysis
Background Structural retinal imaging biomarkers are important for early recognition and
monitoring of inflammation and neurodegeneration in multiple sclerosis. With the …
monitoring of inflammation and neurodegeneration in multiple sclerosis. With the …
Optical coherence tomography in multiple sclerosis: a 3‐year prospective multicenter study
Objective To evaluate changes over 3 years in the thickness of inner retinal layers including
the peripapillary retinal nerve fiber layer (pRNFL), and combined macular ganglion cell and …
the peripapillary retinal nerve fiber layer (pRNFL), and combined macular ganglion cell and …
Optical coherence tomography in multiple sclerosis
J Britze, JL Frederiksen - Eye, 2018 - nature.com
To summarize recent findings regarding the utility of optical coherence tomography in
multiple sclerosis. We searched PubMed for relevant articles using the keywords 'optical …
multiple sclerosis. We searched PubMed for relevant articles using the keywords 'optical …
Retinal thickness measured with optical coherence tomography and risk of disability worsening in multiple sclerosis: a cohort study
EH Martinez-Lapiscina, S Arnow, JA Wilson… - The Lancet …, 2016 - thelancet.com
Background Most patients with multiple sclerosis without previous optic neuritis have thinner
retinal layers than healthy controls. We assessed the role of peripapillary retinal nerve fibre …
retinal layers than healthy controls. We assessed the role of peripapillary retinal nerve fibre …
Optimal intereye difference thresholds by optical coherence tomography in multiple sclerosis: an international study
Objective To determine the optimal thresholds for intereye differences in retinal nerve fiber
and ganglion cell+ inner plexiform layer thicknesses for identifying unilateral optic nerve …
and ganglion cell+ inner plexiform layer thicknesses for identifying unilateral optic nerve …
Clinical implications of serum neurofilament in newly diagnosed MS patients: a longitudinal multicentre cohort study
Background We aim to evaluate serum neurofilament light chain (sNfL), indicating
neuroaxonal damage, as a biomarker at diagnosis in a large cohort of early multiple …
neuroaxonal damage, as a biomarker at diagnosis in a large cohort of early multiple …