[HTML][HTML] The role of gut microbiota in T cell immunity and immune mediated disorders

JA Shim, JH Ryu, Y Jo, C Hong - International journal of biological …, 2023 - ncbi.nlm.nih.gov
Gut microbiota was only considered as a commensal organism that aids in digestion, but
recent studies revealed that the microbiome play a critical role in both physiological and …

Skin immune sentinels in health and disease

FO Nestle, P Di Meglio, JZ Qin… - Nature Reviews …, 2009 - nature.com
Human skin and its immune cells provide essential protection of the human body from injury
and infection. Recent studies reinforce the importance of keratinocytes as sensors of danger …

Vγ1 and Vγ4 gamma-delta T cells play opposing roles in the immunopathology of traumatic brain injury in males

H Abou-El-Hassan, RM Rezende, S Izzy… - Nature …, 2023 - nature.com
Traumatic brain injury (TBI) is a leading cause of morbidity and mortality. The innate and
adaptive immune responses play an important role in the pathogenesis of TBI. Gamma-delta …

The IL-23/T17 pathogenic axis in psoriasis is amplified by keratinocyte responses

MA Lowes, CB Russell, DA Martin, JE Towne… - Trends in …, 2013 - cell.com
Psoriasis is a complex inflammatory process resulting from activation of the well-defined
interleukin (IL)-23/T17 cytokine axis. We review the role of key cytokines IL-17 and IL-23 in …

Immunologic aspects of chronic obstructive pulmonary disease

MG Cosio, M Saetta, A Agusti - New England Journal of Medicine, 2009 - Mass Medical Soc
This review is an account of how pulmonary damage caused by cigarette smoke and other
environmental toxins can incite inflammatory and immunologic reactions that culminate in …

Interleukin-17-producing γδ T cells selectively expand in response to pathogen products and environmental signals

B Martin, K Hirota, DJ Cua, B Stockinger, M Veldhoen - Immunity, 2009 - cell.com
Summary γδ T cells are an innate source of interleukin-17 (IL-17), preceding the
development of the adaptive T helper 17 (Th17) cell response. Here we show that IL-17 …

Chimeric antigen receptors T cell therapy in solid tumor: challenges and clinical applications

HR Mirzaei, A Rodriguez, J Shepphird… - Frontiers in …, 2017 - frontiersin.org
Adoptive cellular immunotherapy (ACT) employing engineered T lymphocytes expressing
chimeric antigen receptors (CARs) has demonstrated promising antitumor effects in …

Estimating T-cell repertoire diversity: limitations of classical estimators and a new approach

DJ Laydon, CRM Bangham… - … Transactions of the …, 2015 - royalsocietypublishing.org
A highly diverse T-cell receptor (TCR) repertoire is a fundamental property of an effective
immune system, and is associated with efficient control of viral infections and other …

The periodontal war: microbes and immunity

JL Ebersole, D Dawson III, P Emecen‐Huja… - Periodontology …, 2017 - Wiley Online Library
Maintenance of periodontal health or transition to a periodontal lesion reflects the
continuous and ongoing battle between the vast microbial ecology in the oral cavity and the …

Skin immunity

A Matejuk - Archivum immunologiae et therapiae experimentalis, 2018 - Springer
Skin is the largest organ of the body with a complex network of multitude of cell types that
perform plastic and dynamic cellular communication to maintain several vital processes …