The GABAergic system in Alzheimer's disease: a systematic review with meta-analysis

G Carello-Collar, B Bellaver, PCL Ferreira… - Molecular …, 2023 - nature.com
The γ-aminobutyric acid (GABA) ergic system is the primary inhibitory neurotransmission
system in the mammalian brain. Its dysregulation has been shown in multiple brain …

The glutamatergic system in Alzheimer's disease: a systematic review with meta-analysis

C Soares, LU Da Ros, LS Machado, A Rocha… - Molecular …, 2024 - nature.com
Glutamatergic neurotransmission system dysregulation may play an important role in the
pathophysiology of Alzheimer's disease (AD). However, reported results on glutamatergic …

Electroconvulsive therapy-specific volume changes in nuclei of the amygdala and their relationship to long-term anxiety improvement in depression

Y Ishikawa, N Oishi, Y Kyuragi, M Hatakoshi… - Molecular …, 2024 - nature.com
Electroconvulsive therapy (ECT) is one of the most effective treatments for depression. ECT
induces volume changes in the amygdala, a key center of anxiety. However, the clinical …

Loss of sodium leak channel (NALCN) in the ventral dentate gyrus impairs neuronal activity of the glutamatergic neurons for inflammation-induced depression in male …

J Wang, Y Yang, J Liu, J Qiu, D Zhang, M Ou… - Brain, Behavior, and …, 2023 - Elsevier
Background The dentate gyrus (DG) has been implicated in the pathophysiology of
depression. Many studies have revealed the cellular types, neural circuits, and …

Neurogenesis-independent mechanisms of MRI-detectable hippocampal volume increase following electroconvulsive stimulation

Y Abe, K Yokoyama, T Kato, S Yagishita… - …, 2024 - nature.com
Electroconvulsive therapy (ECT) is one of the most effective psychiatric treatments but the
underlying mechanisms are still unclear. In vivo human magnetic resonance imaging (MRI) …

MRI textural plasticity in limbic gray matter associated with clinical response to electroconvulsive therapy for psychosis

E Choe, M Kim, S Choi, H Oh, M Jang, S Park… - Molecular …, 2024 - nature.com
Electroconvulsive therapy (ECT) is effective against treatment-resistant psychosis, but its
mechanisms remain unclear. Conventional volumetry studies have revealed plasticity in …

Functional connectivity changes between amygdala and prefrontal cortex after ECT are associated with improvement in distinct depressive symptoms

AK Domke, M Hempel, C Hartling, A Stippl… - European Archives of …, 2023 - Springer
Electroconvulsive therapy (ECT) is one of the most effective treatments for treatment-
resistant depression. However, the underlying mechanisms of action are not yet fully …

Electroconvulsive therapy for treatment-resistant depression

MH Hsieh - Progress in Brain Research, 2023 - Elsevier
Electroconvulsive therapy (ECT), the oldest brain stimulation procedure in psychiatry, is
associated with rapid response and remission in majority of patients with resistant, severe …

Distinct and shared patterns of brain plasticity during electroconvulsive therapy and treatment as usual in depression: an observational multimodal MRI-study

T Bracht, S Walther, S Breit, N Mertse… - Translational …, 2023 - nature.com
Electroconvulsive therapy (ECT) is a highly effective treatment for depression. Previous
studies point to ECT-induced volume increase in the hippocampi and amygdalae, and to …

Brain structural changes underlying clinical symptom improvement following fast-acting treatments in treatment resistant depression

Z Long, J Li, M Marino - Journal of Affective Disorders, 2025 - Elsevier
Background Electroconvulsive therapy (ECT), ketamine infusion (KI), and total sleep
deprivation (TSD) are effective and fast in treating patients with treatment-resistant …