[HTML][HTML] Fibrin clot properties and thrombus composition in cirrhosis

EG Driever, T Lisman - Research and practice in thrombosis and …, 2023 - Elsevier
Patients with cirrhosis frequently acquire profound hemostatic alterations, which may affect
thrombus quality and composition—factors that determine the susceptibility to embolization …

Fibrinolysis-mediated pathways in acute liver injury

GE Capece, JP Luyendyk… - Seminars in Thrombosis …, 2024 - thieme-connect.com
Acute liver injury (ALI), that is, the development of reduced liver function in patients without
preexisting liver disease, can result from a wide range of causes, such as viral or bacterial …

SARS‐CoV‐2 infection induces soluble platelet activation markers and PAI‐1 in the early moderate stage of COVID‐19

AO Al‐Tamimi, AM Yusuf… - International Journal …, 2022 - Wiley Online Library
Introduction Coagulation dysfunction and thromboembolism emerge as strong comorbidity
factors in severe COVID‐19. However, it is unclear when particularly platelet activation …

Robust coagulation activation and coagulopathy in mice with experimental acetaminophen-induced liver failure

DJ Groeneveld, LG Poole, EG Bouck, A Schulte… - Journal of Thrombosis …, 2023 - Elsevier
Background Patients with acetaminophen (APAP)-induced acute liver failure (ALF) display
both hyper-and hypocoagulable changes not necessarily recapitulated by standard …

[HTML][HTML] Thrombus composition and thrombolysis resistance in stroke

B Ho-Tin-Noé, JP Desilles, M Mazighi - Research and Practice in …, 2023 - Elsevier
A State of the Art lecture titled “Thrombus Composition and Thrombolysis Resistance in
Stroke” was presented at the ISTH Congress in 2022. Intravenous thrombolysis (IVT) …

[HTML][HTML] Intraoperative bioprinting of human adipose-derived stem cells and extra-cellular matrix induces hair follicle-like downgrowths and adipose tissue formation …

Y Kang, M Yeo, ID Derman, DJ Ravnic, YP Singh… - Bioactive Materials, 2024 - Elsevier
Craniomaxillofacial (CMF) reconstruction is a challenging clinical dilemma. It often
necessitates skin replacement in the form of autologous graft or flap surgery, which differ …

Elimination of fibrin polymer formation or crosslinking, but not fibrinogen deficiency, is protective against diet‐induced obesity and associated pathologies

WS Hur, KC King, YN Patel, YV Nguyen… - … of Thrombosis and …, 2022 - Wiley Online Library
Background Obesity predisposes individuals to metabolic syndrome, which increases the
risk of cardiovascular diseases, non‐alcoholic fatty liver disease (NAFLD), and type 2 …

[HTML][HTML] Proteomic evidence for amyloidogenic cross-seeding in fibrinaloid microclots

DB Kell, E Pretorius - International Journal of Molecular …, 2024 - pmc.ncbi.nlm.nih.gov
In classical amyloidoses, amyloid fibres form through the nucleation and accretion of protein
monomers, with protofibrils and fibrils exhibiting a cross-β motif of parallel or antiparallel β …

Effects of inflammation on hemostasis in acutely ill patients with liver disease

EG Driever, T Lisman - Seminars in thrombosis and hemostasis, 2022 - thieme-connect.com
Patients with liver diseases are in a rebalanced state of hemostasis, due to simultaneous
decline in pro-and anticoagulant factors. This balance seems to remain even in the sickest …

[HTML][HTML] Cross‐linking by tissue transglutaminase‐2 alters fibrinogen‐directed macrophage proinflammatory activity

LG Poole, AK Kopec, MJ Flick, JP Luyendyk - Journal of Thrombosis and …, 2022 - Elsevier
Background The blood coagulation factor fibrin (ogen) can modulate inflammation by
altering leukocyte activity. Analyses of fibrin (ogen)‐mediated proinflammatory activity have …