Although the first polysarcosine (pSar) synthesis by Wesseley et al. was reported almost a
century ago, it was only recently that pSar gained broader attention and is considered a …

Synthetic peptide-based polymers represent a unique class of macromolecules able to
mimic the properties of natural proteins in materials sciences since (1) they present the …

Hepatocellular carcinoma (HCC) is the most frequent type of primary liver cancer and the
third leading cause for cancer‐related death worldwide. The tumor is difficult‐to‐treat due to …

Polypeptides have broad applications and can be prepared via ring-opening polymerization
of α-amino acid N-carboxyanhydrides (NCAs). Conventional initiators, such as primary …

Polysarcosine (pSar) was one of the first polymers synthesized in a controlled living manner,
but it was only recently when it was reconsidered as a promising alternative for poly …

Mitochondria play critical roles in regulating cell fate, with dysfunction correlating with the
development of multiple diseases, emphasizing the need for engineered nanomedicines …

Polypeptides are envisaged to achieve a major impact on a number of different relevant
areas such as biomedicine and biotechnology. Acquired knowledge and the increasing …

The development of novel reagents and antibiotics for combating multidrug resistance
bacteria has received significant attention in recent years. In this study, new antimicrobial …

Cylindrical brush polymers constitute promising polymeric drug delivery systems
(nanoDDS). Because of the densely grafted side chains such structures may intrinsically …

A series of four-arm star copolymers, incorporating glycopolymer and antimicrobial
polypeptide domains, was developed in the design of forthcoming anti-infective agents …