The past decade has witnessed exponentially growing interest in the lateral habenula (LHb)
owing to new discoveries relating to its critical role in regulating negatively motivated …

Aggression is a social behavior essential for securing resources and defending oneself and
family. Thanks to its indispensable function in competition and thus survival, aggression …

Studies suggest that heightened peripheral inflammation contributes to the pathogenesis of
major depressive disorder. We investigated the effect of chronic social defeat stress, a …

Social behaviors are among the most important motivated behaviors. How dopamine (DA),
a" reward" signal, releases during social behaviors has been a topic of interest for decades …

We live in a world that is largely socially constructed, and we are constantly involved in and
fundamentally influenced by a broad array of complex social interactions. Social behaviors …

Downward social mobility is a well-known mental risk factor for depression, but its neural
mechanism remains elusive. Here, by forcing mice to lose against their subordinates in a …

Social interactions and relationships are often rewarding, but the neural mechanisms
through which social interaction drives positive experience remain poorly understood. In this …

Social stress can lead to the development of psychological problems ranging from
exaggerated anxiety and depression to antisocial and violence-related behaviors …

Social homeostasis is the ability of individuals to detect the quantity and quality of social
contact, compare it to an established set-point in a command center, and adjust the effort …

Septal-hypothalamic neuronal activity centrally mediates aggressive behavior and
dopamine system hyperactivity is associated with elevated aggression. However, the causal …