Cadherin signaling in cancer: its functions and role as a therapeutic target
W Yu, L Yang, T Li, Y Zhang - Frontiers in oncology, 2019 - frontiersin.org
Cadherin family includes lists of transmembrane glycoproteins which mediate calcium-
dependent cell-cell adhesion. Cadherin-mediated adhesion regulates cell growth and …
dependent cell-cell adhesion. Cadherin-mediated adhesion regulates cell growth and …
Lobular breast cancer: histomorphology and different concepts of a special spectrum of tumors
Simple Summary Invasive lobular breast cancer (ILC) is a special type of breast cancer (BC)
that was first described in 1941. The diagnosis of ILC is made by microscopy of tumor …
that was first described in 1941. The diagnosis of ILC is made by microscopy of tumor …
The role of hypoxia and SRC tyrosine kinase in glioblastoma invasiveness and radioresistance
F Torrisi, N Vicario, FM Spitale, FP Cammarata… - Cancers, 2020 - mdpi.com
Simple Summary The biological pathways underlying glioblastoma malignancy and
radioresistance are still unclear. In this review, we describe the role of the hypoxic …
radioresistance are still unclear. In this review, we describe the role of the hypoxic …
Role of cell division cycle-associated proteins in regulating cell cycle and promoting tumor progression
Z Wang, M Ren, W Liu, J Wu, P Tang - Biochimica et Biophysica Acta (BBA) …, 2024 - Elsevier
The cell division cycle-associated protein (CDCA) family is important in regulating cell
division. High CDCA expression is significantly linked to tumor development. This review …
division. High CDCA expression is significantly linked to tumor development. This review …
The prognostic significance of interferon-stimulated gene 15 (ISG15) in invasive breast cancer
Background Lymphovascular invasion (LVI) is a prognostic factor in early-stage invasive
breast cancer (BC). Through bioinformatics, data analyses of multiple BC cohorts revealed …
breast cancer (BC). Through bioinformatics, data analyses of multiple BC cohorts revealed …
Prognostic value of a stemness index-associated signature in primary lower-grade glioma
M Zhang, X Wang, X Chen, F Guo, J Hong - Frontiers in Genetics, 2020 - frontiersin.org
Objective As a prevalent and infiltrative cancer type of the central nervous system, the
prognosis of lower-grade glioma (LGG) in adults is highly heterogeneous. Recent evidence …
prognosis of lower-grade glioma (LGG) in adults is highly heterogeneous. Recent evidence …
Clinical and molecular significance of the RNA m6A methyltransferase complex in prostate cancer
J Lothion-Roy, DB Haigh, AE Harris, VM Metzler… - Frontiers in …, 2023 - frontiersin.org
N6-methyladenosine (m6A) is the most abundant internal mRNA modification and is
dynamically regulated through distinct protein complexes that methylate, demethylate …
dynamically regulated through distinct protein complexes that methylate, demethylate …
Genomic and epigenomic basis of breast invasive lobular carcinomas lacking CDH1 genetic alterations
Abstract CDH1 (E-cadherin) bi-allelic inactivation is the hallmark alteration of breast invasive
lobular carcinoma (ILC), resulting in its discohesive phenotype. A subset of ILCs, however …
lobular carcinoma (ILC), resulting in its discohesive phenotype. A subset of ILCs, however …
[HTML][HTML] Bio-Pathological Functions of Posttranslational Modifications of Histological Biomarkers in Breast Cancer
Proteins are the most common types of biomarkers used in breast cancer (BC) theranostics
and management. By definition, a biomarker must be a relevant, objective, stable, and …
and management. By definition, a biomarker must be a relevant, objective, stable, and …
Ubiquitin-conjugating enzyme 2C (UBE2C) is a poor prognostic biomarker in invasive breast cancer
Abstract Background The Ubiquitin-conjugating enzyme 2C (UBE2C) is essential for the
ubiquitin–proteasome system and is involved in cancer cell migration and apoptosis. This …
ubiquitin–proteasome system and is involved in cancer cell migration and apoptosis. This …