Connected healthcare: Improving patient care using digital health technologies

A Awad, SJ Trenfield, TD Pollard, JJ Ong… - Advanced Drug Delivery …, 2021‏ - Elsevier
Now more than ever, traditional healthcare models are being overhauled with digital
technologies of Healthcare 4.0 increasingly adopted. Worldwide, digital devices are …

[HTML][HTML] Colonic drug delivery: Formulating the next generation of colon-targeted therapeutics

LE McCoubrey, A Favaron, A Awad, M Orlu… - Journal of Controlled …, 2023‏ - Elsevier
Colonic drug delivery can facilitate access to unique therapeutic targets and has the
potential to enhance drug bioavailability whilst reducing off-target effects. Delivering drugs to …

Advancing pharmacy and healthcare with virtual digital technologies

SJ Trenfield, A Awad, LE McCoubrey… - Advanced Drug Delivery …, 2022‏ - Elsevier
Digitalisation of the healthcare sector promises to revolutionise patient healthcare globally.
From the different technologies, virtual tools including artificial intelligence, blockchain …

Machine learning predicts 3D printing performance of over 900 drug delivery systems

BM Castro, M Elbadawi, JJ Ong, T Pollard… - Journal of Controlled …, 2021‏ - Elsevier
Abstract Three-dimensional printing (3DP) is a transformative technology that is advancing
pharmaceutical research by producing personalized drug products. However, advances …

Machine learning and artificial intelligence in toxicological sciences

Z Lin, WC Chou - Toxicological Sciences, 2022‏ - academic.oup.com
Abstract Machine learning and artificial intelligence approaches have revolutionized
multiple disciplines, including toxicology. This review summarizes representative recent …

Clinical translation of advanced colonic drug delivery technologies

A Awad, CM Madla, LE McCoubrey, F Ferraro… - Advanced drug delivery …, 2022‏ - Elsevier
Targeted drug delivery to the colon offers a myriad of benefits, including treatment of local
diseases, direct access to unique therapeutic targets and the potential for increasing …

A review of state-of-the-art on enabling additive manufacturing processes for precision medicine

A Awad, A Goyanes, AW Basit… - Journal of …, 2023‏ - asmedigitalcollection.asme.org
Precision medicine is an emerging healthcare delivery approach that considers variability
between patients, such as genetic makeups, in contrast to the current one-size-fits-all …

Predicting drug-microbiome interactions with machine learning

LE McCoubrey, S Gaisford, M Orlu, AW Basit - Biotechnology advances, 2022‏ - Elsevier
Pivotal work in recent years has cast light on the importance of the human microbiome in
maintenance of health and physiological response to drugs. It is now clear that …

A graph neural network approach for predicting drug susceptibility in the human microbiome

MU Rehman, I Hussain, H Tayara, KT Chong - Computers in Biology and …, 2024‏ - Elsevier
Recent studies have illuminated the critical role of the human microbiome in maintaining
health and influencing the pharmacological responses of drugs. Clinical trials …

The interplay between gut microbiota and oral medications and its impact on advancing precision medicine

S Mousa, M Sarfraz, WK Mousa - Metabolites, 2023‏ - mdpi.com
Trillions of diverse microbes reside in the gut and are deeply interwoven with the human
physiological process, from food digestion, immune system maturation, and fighting invading …