Osmotic pressure and its biological implications

S Zheng, Y Li, Y Shao, L Li, F Song - International Journal of Molecular …, 2024 - mdpi.com
Gaining insight into osmotic pressure and its biological implications is pivotal for revealing
mechanisms underlying numerous fundamental biological processes across scales and will …

Intercellular receptor-ligand binding: Effect of protein-membrane interaction

L Li, J Ji, F Song, J Hu - Journal of Molecular Biology, 2023 - Elsevier
Gaining insights into the intercellular receptor-ligand binding is of great importance for
understanding numerous physiological and pathological processes, and stimulating new …

Capturing phase behavior of ternary lipid mixtures with a refined martini coarse-grained force field

TS Carpenter, CA López, C Neale… - Journal of chemical …, 2018 - ACS Publications
Whether lipid rafts are present in the membranes of living cells remains hotly disputed
despite their incontrovertible existence in liposomes at 298 K. In attempts to resolve this …

Control of cell membrane receptor condensation by adhesion to supported bilayers with nanoscale topography

L Li, R Hou, X Shi, J Ji, B Różycki, J Hu… - Communications …, 2024 - nature.com
Develo** physical methods to modulate biomolecular clusters and condensates on cell
membranes is of great importance for understanding physiological and pathological …

The interplay between membrane viscosity and ligand-binding receptor kinetics in lipid bilayers

C Bernard, AR Carotenuto, NM Pugno, L Deseri… - Meccanica, 2024 - Springer
Plasma membranes appear as deformable systems wherein molecules are free to move and
diffuse giving rise to condensed microdomains (composed of ordered lipids, transmembrane …

Receptor–ligand binding: Effect of mechanical factors

R Du, L Li, J Ji, Y Fan - International Journal of Molecular Sciences, 2023 - mdpi.com
Gaining insight into the in situ receptor–ligand binding is pivotal for revealing the molecular
mechanisms underlying the physiological and pathological processes and will contribute to …

[HTML][HTML] Membrane-Mediated Cooperative Interactions of CD47 and SIRPα

L Li, C Gui, J Hu, B Różycki - Membranes, 2023 - mdpi.com
The specific binding of the ubiquitous 'marker of self'protein CD47 to the SIRP α protein
anchored in the macrophage plasma membrane results in the inhibition of the engulfment of …

Interplay between cooperativity of intercellular receptor–ligand binding and coalescence of nanoscale lipid clusters in adhering membranes

L Li, J Hu, X Shi, B Różycki, F Song - Soft Matter, 2021 - pubs.rsc.org
Adhesion of biological cells is mediated by the specific binding of receptors and ligands
which are typically large proteins spanning through the plasma membranes of the contacting …

Modelling lipid rafts formation through chemo-mechanical interplay triggered by receptor–ligand binding

C Bernard, AR Carotenuto, NM Pugno, M Fraldi… - … and Modeling in …, 2024 - Springer
Cell membranes, mediator of many biological mechanisms from adhesion and metabolism
up to mutation and infection, are highly dynamic and heterogeneous environments …

Intercellular receptor–ligand binding and thermal fluctuations facilitate receptor aggregation in adhering membranes

L Li, J Hu, B Różycki, F Song - Nano letters, 2019 - ACS Publications
Nanoscale molecular clusters in cell membranes can serve as platforms to recruit
membrane proteins for various biological functions. A central question is how these …