Reviewing the history of pandemic influenza: understanding patterns of emergence and transmission

PR Saunders-Hastings, D Krewski - Pathogens, 2016 - mdpi.com
For centuries, novel strains of influenza have emerged to produce human pandemics,
causing widespread illness, death, and disruption. There have been four influenza …

Understanding dynamics of pandemics

L Akin, MG Gözel - Turkish journal of medical sciences, 2020 - journals.tubitak.gov.tr
Along the centuries, novel strain of virus such as influenza produces pandemics which
increase illness, death and disruption in the countries. Spanish flu in 1918, Asian flu in 1957 …

Structural basis of influenza virus fusion inhibition by the antiviral drug Arbidol

RU Kadam, IA Wilson - Proceedings of the National …, 2017 - National Acad Sciences
The broad-spectrum antiviral drug Arbidol shows efficacy against influenza viruses by
targeting the hemagglutinin (HA) fusion machinery. However, the structural basis of the …

[HTML][HTML] Comparative community burden and severity of seasonal and pandemic influenza: results of the Flu Watch cohort study

AC Hayward, EB Fragaszy, A Bermingham… - The Lancet …, 2014 - thelancet.com
Background Assessment of the effect of influenza on populations, including risk of infection,
illness if infected, illness severity, and consultation rates, is essential to inform future control …

An overview of influenza viruses and vaccines

RF Nuwarda, AA Alharbi, V Kayser - Vaccines, 2021 - mdpi.com
Influenza remains one of the major public health concerns because it causes annual
epidemics and can potentially instigate a global pandemic. Numerous countermeasures …

Estimation of potential global pandemic influenza mortality on the basis of vital registry data from the 1918–20 pandemic: a quantitative analysis

CJL Murray, AD Lopez, B Chin, D Feehan, KH Hill - The Lancet, 2006 - thelancet.com
Background The threat of an avian influenza pandemic is causing widespread public
concern and health policy response, especially in high-income countries. Our aim was to …

Fifty years of influenza A (H3N2) following the pandemic of 1968

BJ Jester, TM Uyeki… - American journal of …, 2020 - ajph.aphapublications.org
In 2018, the world commemorated the centennial of the 1918 influenza A (H1N1) pandemic,
the deadliest pandemic in recorded history; however, little mention was made of the 50th …

The socio-economic determinants of the coronavirus disease (COVID-19) pandemic

V Stojkoski, Z Utkovski, P Jolakoski, D Tevdovski… - MedRxiv, 2020 - medrxiv.org
The magnitude of the coronavirus disease (COVID-19) pandemic has an enormous impact
on the social life and the economic activities in almost every country in the world. Besides …

A single mutation in the PB1-F2 of H5N1 (HK/97) and 1918 influenza A viruses contributes to increased virulence

GM Conenello, D Zamarin, LA Perrone… - PLoS …, 2007 - journals.plos.org
The proapoptotic PB1-F2 protein of influenza A viruses has been shown to contribute to
pathogenesis in the mouse model. Expression of full-length PB1-F2 increases the …

The 1918 “spanish flu” in spain

A Trilla, G Trilla, C Daer - Clinical infectious diseases, 2008 - academic.oup.com
The 1918–1919 influenza pandemic was the most devastating epidemic in modern history.
Here, we review epidemiological and historical data about the 1918–1919 influenza …