Innate immunity in diabetes and diabetic nephropathy

J Wada, H Makino - Nature Reviews Nephrology, 2016 - nature.com
The innate immune system includes several classes of pattern recognition receptors (PRRs),
including membrane-bound Toll-like receptors (TLRs) and nucleotide-binding …

The impact of maternal high-fat diet on offspring neurodevelopment

G Urbonaite, A Knyzeliene, FS Bunn… - Frontiers in …, 2022 - frontiersin.org
A maternal high-fat diet affects offspring neurodevelopment with long-term consequences on
their brain health and behavior. During the past three decades, obesity has rapidly …

Western diet induces dysbiosis with increased E coli in CEABAC10 mice, alters host barrier function favouring AIEC colonisation

M Martinez-Medina, J Denizot, N Dreux, F Robin… - Gut, 2014 - gut.bmj.com
Objective Western diet is a risk factor for Crohn's disease (CD). Carcinoembryonic antigen-
related cell adhesion molecule 6 (CEACAM6) is abnormally expressed in CD patients. This …

Obesity phenotype is related to NLRP3 inflammasome activity and immunological profile of visceral adipose tissue

N Esser, L L'homme, A De Roover, L Kohnen… - Diabetologia, 2013 - Springer
Aims/hypothesis Obesity is a heterogeneous condition comprising both individuals who
remain metabolically healthy (MHO) and those who develop metabolic disorders …

The role of lipids in the regulation of immune responses

C Garcia, CJ Andersen, CN Blesso - Nutrients, 2023 - mdpi.com
Lipid metabolism plays a major role in the regulation of the immune system. Exogenous
(dietary and microbial-derived) and endogenous (non-microbial-derived) lipids play a direct …

The biomedical uses of inositols: A nutraceutical approach to metabolic dysfunction in aging and neurodegenerative diseases

AJ López-Gambero, C Sanjuan, PJ Serrano-Castro… - Biomedicines, 2020 - mdpi.com
Inositols are sugar-like compounds that are widely distributed in nature and are a part of
membrane molecules, participating as second messengers in several cell-signaling …

[HTML][HTML] Impaired hepatic vitamin A metabolism in NAFLD mice leading to vitamin A accumulation in hepatocytes

A Saeed, P Bartuzi, J Heegsma, D Dekker… - Cellular and molecular …, 2021 - Elsevier
Background & Aims Systemic retinol (vitamin A) homeostasis is controlled by the liver,
involving close collaboration between hepatocytes and hepatic stellate cells (HSCs) …

Nutrition, inflammation and liver-spleen axis

L Barrea, C Di Somma, G Muscogiuri… - Critical Reviews in …, 2018 - Taylor & Francis
Chronic low-grade systemic inflammation represents a mechanism common to many
diseases linked to atherosclerosis-related pathways. There is a growing body of evidence …

Role of extrathyroidal TSHR expression in adipocyte differentiation and its association with obesity

S Lu, Q Guan, Y Liu, H Wang, W Xu, X Li, Y Fu… - Lipids in health and …, 2012 - Springer
Background Obesity is known to be associated with higher risks of cardiovascular disease,
metabolic syndrome, and diabetes mellitus. Thyroid-stimulating hormone (TSHR) is the …

IBD: in food we trust

R Marion-Letellier, G Savoye… - Journal of Crohn's and …, 2016 - academic.oup.com
Abstract Background and Aims: Both science and patients associate diet with inflammatory
bowel disease [IBD]. There is no doubt that links between IBD and diet are numerous, based …