Learning from metabolic networks: Current trends and future directions for precision medicine

I Granata, M Manzo, A Kusumastuti… - Current Medicinal …, 2021 - ingentaconnect.com
Background: Systems biology and network modeling represent, nowadays, the hallmark
approaches for the development of predictive and targeted-treatment based precision …

Stability of signaling pathways during aging—a Boolean network approach

JD Schwab, L Siegle, SD Kühlwein, M Kühl, HA Kestler - Biology, 2017 - mdpi.com
Biological pathways are thought to be robust against a variety of internal and external
perturbations. Fail-safe mechanisms allow for compensation of perturbations to maintain the …

A systems biology approach to define mechanisms, phenotypes, and drivers in PanNETs with a personalized perspective

SD Werle, N Ikonomi, L Lausser… - npj Systems Biology …, 2023 - nature.com
Pancreatic neuroendocrine tumors (PanNETs) are a rare tumor entity with largely
unpredictable progression and increasing incidence in developed countries. Molecular …

Logical modelling of molecular crosstalks for the prediction of complex phenotypes

N Ikonomi - 2023 - oparu.uni-ulm.de
Abstract Systems biology investigates the understanding of complex biological processes,
such as ageing or cancer, by integrating a holistic view, which is mostly unconsidered when …

Artificial RNA motifs expand the programmable assembly between RNA modules of a bimolecular ribozyme leading to application to RNA nanostructure design

MM Rahman, S Matsumura, Y Ikawa - Biology, 2017 - mdpi.com
A bimolecular ribozyme consisting of a core ribozyme (ΔP5 RNA) and an activator module
(P5abc RNA) has been used as a platform to design assembled RNA nanostructures. The …

CRNet Translator: Building GMA, S-System Models and Chemical Reaction Networks of Disease and Metabolic Pathways

KT Fields, N Fortun, GA Solano… - 2020 11th International …, 2020 - ieeexplore.ieee.org
Ordinary Differential Equation (ODE) requires the use of differential equations to describe
the dynamically changing phenomena, evolution, and variation and Chemical Reaction …

[PDF][PDF] Understanding azathioprine metabolism using a systems pharmacology approach

VK Siripuram - 2019 - ourarchive.otago.ac.nz
Quantitative systems pharmacology (QSP) modelling, being an integral part of
pharmacometrics, is attracting a great amount of attention in drug development and clinical …

[CITATION][C] Метод доминантного параметра в моделировании и анализе динамики биологических осцилляторов

АИ Лаврова - 2018 - elib.spbstu.ru
ЭБ СПбПУ - Метод доминантного параметра в моделировании и анализе динамики
биологических осцилляторов: автореф.... Logo Расширенный поиск Атрибутный поиск …