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The fibroblast growth factor signaling pathway
DM Ornitz, N Itoh - Wiley Interdisciplinary Reviews …, 2015 - Wiley Online Library
The signaling component of the mammalian Fibroblast Growth Factor (FGF) family is
comprised of eighteen secreted proteins that interact with four signaling tyrosine kinase FGF …
comprised of eighteen secreted proteins that interact with four signaling tyrosine kinase FGF …
The impact of transposable elements in adaptive evolution
The growing knowledge about the influence of transposable elements (TE s) on (a) long‐
term genome and transcriptome evolution;(b) genomic, transcriptomic and epigenetic …
term genome and transcriptome evolution;(b) genomic, transcriptomic and epigenetic …
Ancestry-inclusive dog genomics challenges popular breed stereotypes
Behavioral genetics in dogs has focused on modern breeds, which are isolated subgroups
with distinctive physical and, purportedly, behavioral characteristics. We interrogated breed …
with distinctive physical and, purportedly, behavioral characteristics. We interrogated breed …
Genome sequencing of 2000 canids by the Dog10K consortium advances the understanding of demography, genome function and architecture
Abstract Background The international Dog10K project aims to sequence and analyze
several thousand canine genomes. Incorporating 20× data from 1987 individuals, including …
several thousand canine genomes. Incorporating 20× data from 1987 individuals, including …
Genomic and archaeological evidence suggest a dual origin of domestic dogs
The geographic and temporal origins of dogs remain controversial. We generated genetic
sequences from 59 ancient dogs and a complete (28x) genome of a late Neolithic dog …
sequences from 59 ancient dogs and a complete (28x) genome of a late Neolithic dog …
[HTML][HTML] Genomic analyses reveal the influence of geographic origin, migration, and hybridization on modern dog breed development
There are nearly 400 modern domestic dog breeds with a unique histories and genetic
profiles. To track the genetic signatures of breed development, we have assembled the most …
profiles. To track the genetic signatures of breed development, we have assembled the most …
Rethinking dog domestication by integrating genetics, archeology, and biogeography
The dog was the first domesticated animal but it remains uncertain when the domestication
process began and whether it occurred just once or multiple times across the Northern …
process began and whether it occurred just once or multiple times across the Northern …
Active human retrotransposons: variation and disease
DC Hancks, HH Kazazian Jr - Current opinion in genetics & development, 2012 - Elsevier
Mobile DNAs, also known as transposons or 'jum** genes', are widespread in nature and
comprise an estimated 45% of the human genome. Transposons are divided into two …
comprise an estimated 45% of the human genome. Transposons are divided into two …
The influence of LINE‐1 and SINE retrotransposons on mammalian genomes
Transposable elements (TEs) or “jum** genes” historically have been disparaged as a
class of “junk DNA” in mammalian genomes (1, 2). The advent of whole genome DNA …
class of “junk DNA” in mammalian genomes (1, 2). The advent of whole genome DNA …
Origins, evolution, and phenotypic impact of new genes
H Kaessmann - Genome research, 2010 - genome.cshlp.org
Ever since the pre-molecular era, the birth of new genes with novel functions has been
considered to be a major contributor to adaptive evolutionary innovation. Here, I review the …
considered to be a major contributor to adaptive evolutionary innovation. Here, I review the …