The fibroblast growth factor signaling pathway

DM Ornitz, N Itoh - Wiley Interdisciplinary Reviews …, 2015 - Wiley Online Library
The signaling component of the mammalian Fibroblast Growth Factor (FGF) family is
comprised of eighteen secreted proteins that interact with four signaling tyrosine kinase FGF …

The impact of transposable elements in adaptive evolution

L Schrader, J Schmitz - Molecular Ecology, 2019 - Wiley Online Library
The growing knowledge about the influence of transposable elements (TE s) on (a) long‐
term genome and transcriptome evolution;(b) genomic, transcriptomic and epigenetic …

Ancestry-inclusive dog genomics challenges popular breed stereotypes

K Morrill, J Hekman, X Li, J McClure, B Logan… - Science, 2022 - science.org
Behavioral genetics in dogs has focused on modern breeds, which are isolated subgroups
with distinctive physical and, purportedly, behavioral characteristics. We interrogated breed …

Genome sequencing of 2000 canids by the Dog10K consortium advances the understanding of demography, genome function and architecture

JRS Meadows, JM Kidd, GD Wang, HG Parker… - Genome biology, 2023 - Springer
Abstract Background The international Dog10K project aims to sequence and analyze
several thousand canine genomes. Incorporating 20× data from 1987 individuals, including …

Genomic and archaeological evidence suggest a dual origin of domestic dogs

LAF Frantz, VE Mullin, M Pionnier-Capitan… - Science, 2016 - science.org
The geographic and temporal origins of dogs remain controversial. We generated genetic
sequences from 59 ancient dogs and a complete (28x) genome of a late Neolithic dog …

[HTML][HTML] Genomic analyses reveal the influence of geographic origin, migration, and hybridization on modern dog breed development

HG Parker, DL Dreger, M Rimbault, BW Davis… - Cell reports, 2017 - cell.com
There are nearly 400 modern domestic dog breeds with a unique histories and genetic
profiles. To track the genetic signatures of breed development, we have assembled the most …

Rethinking dog domestication by integrating genetics, archeology, and biogeography

G Larson, EK Karlsson, A Perri, MT Webster… - Proceedings of the …, 2012 - pnas.org
The dog was the first domesticated animal but it remains uncertain when the domestication
process began and whether it occurred just once or multiple times across the Northern …

Active human retrotransposons: variation and disease

DC Hancks, HH Kazazian Jr - Current opinion in genetics & development, 2012 - Elsevier
Mobile DNAs, also known as transposons or 'jum** genes', are widespread in nature and
comprise an estimated 45% of the human genome. Transposons are divided into two …

The influence of LINE‐1 and SINE retrotransposons on mammalian genomes

SR Richardson, AJ Doucet, HC Kopera… - Mobile DNA …, 2015 - Wiley Online Library
Transposable elements (TEs) or “jum** genes” historically have been disparaged as a
class of “junk DNA” in mammalian genomes (1, 2). The advent of whole genome DNA …

Origins, evolution, and phenotypic impact of new genes

H Kaessmann - Genome research, 2010 - genome.cshlp.org
Ever since the pre-molecular era, the birth of new genes with novel functions has been
considered to be a major contributor to adaptive evolutionary innovation. Here, I review the …