Current advance of nanotechnology in diagnosis and treatment for malignant tumors

B Wang, S Hu, Y Teng, J Chen, H Wang, Y Xu… - … and Targeted Therapy, 2024 - nature.com
Cancer remains a significant risk to human health. Nanomedicine is a new multidisciplinary
field that is garnering a lot of interest and investigation. Nanomedicine shows great potential …

Microfluidic formulation of nanoparticles for biomedical applications

SJ Shepherd, D Issadore, MJ Mitchell - Biomaterials, 2021 - Elsevier
Nanomedicine has made significant advances in clinical applications since the late-20th
century, in part due to its distinct advantages in biocompatibility, potency, and novel …

Exploring dendrimer-based drug delivery systems and their potential applications in cancer immunotherapy

S Mukherjee, S Mukherjee, MAS Abourehab… - European Polymer …, 2022 - Elsevier
Cancer immunotherapy has been researched as a major modality of treatment which
involves activating the immune system of the patient to fight against tumor cells. Dendrimers …

Biocompatibility of nanomaterials and their immunological properties

TR Kyriakides, A Raj, TH Tseng, H **ao… - Biomedical …, 2021 - iopscience.iop.org
Nanomaterials (NMs) have revolutionized multiple aspects of medicine by enabling novel
sensing, diagnostic, and therapeutic approaches. Advancements in processing and …

Bioinspired and biomimetic micro-and nanostructures in biomedicine

AP Johnson, C Sabu, KP Nivitha, R Sankar… - Journal of Controlled …, 2022 - Elsevier
Bioinspired and biomimetic micro-and nanostructures have a high significance in the field of
biomedicine. In this review, the possible applications of these micro-and nanostructures that …

Ionizable lipid nanoparticle-mediated TRAIL mRNA delivery in the tumor microenvironment to inhibit colon cancer progression

WN da Silva, PA Carvalho Costa… - International Journal …, 2024 - Taylor & Francis
Introduction Immunotherapy has revolutionized cancer treatment by harnessing the immune
system to enhance antitumor responses while minimizing off-target effects. Among the …

Biomaterials for vaccine-based cancer immunotherapy

R Zhang, MM Billingsley, MJ Mitchell - Journal of Controlled Release, 2018 - Elsevier
The development of therapeutic cancer vaccines as a means to generate immune reactivity
against tumors has been explored since the early discovery of tumor-specific antigens by …

[HTML][HTML] Targeting glucose metabolism in cancer cells as an approach to overcoming drug resistance

A Cunha, PMA Silva, B Sarmento, O Queirós - Pharmaceutics, 2023 - mdpi.com
The “Warburg effect” consists of a metabolic shift in energy production from oxidative
phosphorylation to glycolysis. The continuous activation of glycolysis in cancer cells causes …

TRAIL of hope meeting resistance in cancer

D Deng, K Shah - Trends in cancer, 2020 - cell.com
Tumor necrosis factor (TNF)-related apoptosis-inducing ligand (TRAIL) induces apoptosis
selectively via its interaction with the death receptors TRAILR1/DR4 and TRAILR2/DR5 in a …

Emerging nano‐/microapproaches for cancer immunotherapy

Y Mi, CT Hagan IV, BG Vincent, AZ Wang - Advanced Science, 2019 - Wiley Online Library
Cancer immunotherapy has achieved remarkable clinical efficacy through recent advances
such as chimeric antigen receptor‐T cell (CAR‐T) therapy, immune checkpoint blockade …