Vaccine adjuvants: mechanisms and platforms

T Zhao, Y Cai, Y Jiang, X He, Y Wei, Y Yu… - Signal transduction and …, 2023 - nature.com
Adjuvants are indispensable components of vaccines. Despite being widely used in
vaccines, their action mechanisms are not yet clear. With a greater understanding of the …

Lipid-based nanoparticles in the clinic and clinical trials: from cancer nanomedicine to COVID-19 vaccines

TTH Thi, EJA Suys, JS Lee, DH Nguyen, KD Park… - Vaccines, 2021 - mdpi.com
COVID-19 vaccines have been developed with unprecedented speed which would not have
been possible without decades of fundamental research on delivery nanotechnology. Lipid …

An overview of vaccine adjuvants: current evidence and future perspectives

A Facciolà, G Visalli, A Laganà, A Di Pietro - Vaccines, 2022 - mdpi.com
Vaccinations are one of the most important preventive tools against infectious diseases.
Over time, many different types of vaccines have been developed concerning the antigen …

A global review on short peptides: frontiers and perspectives

V Apostolopoulos, J Bojarska, TT Chai, S Elnagdy… - Molecules, 2021 - mdpi.com
Peptides are fragments of proteins that carry out biological functions. They act as signaling
entities via all domains of life and interfere with protein-protein interactions, which are …

Safety and immunogenicity of S-Trimer (SCB-2019), a protein subunit vaccine candidate for COVID-19 in healthy adults: a phase 1, randomised, double-blind …

P Richmond, L Hatchuel, M Dong, B Ma, B Hu… - The lancet, 2021 - thelancet.com
Background As part of the accelerated development of vaccines against severe acute
respiratory syndrome coronavirus 2 (SARS-CoV-2), we report a dose-finding and adjuvant …

The impact of spike mutated variants of SARS-CoV2 [Alpha, Beta, Gamma, Delta, and Lambda] on the efficacy of subunit recombinant vaccines

M Mohammadi, M Shayestehpour… - Brazilian Journal of …, 2021 - SciELO Brasil
Since the first described human infection with SARS-CoV-2 in December of 2019 many
subunit protein vaccines have been proposed for use in humans. Subunit vaccines use one …

Adjuvant physiochemistry and advanced nanotechnology for vaccine development

H Ren, W Jia, Y ** personalized neoantigen cancer vaccines
PD Katsikis, KJ Ishii, C Schliehe - Nature Reviews Immunology, 2024 - nature.com
The recent success of cancer immunotherapies has highlighted the benefit of harnessing the
immune system for cancer treatment. Vaccines have a long history of promoting immunity to …