Postbiotics: An alternative and innovative intervention for the therapy of inflammatory bowel disease

H Om, U Chand, PK Kushawaha - Microbiological Research, 2024 - Elsevier
Abstract Inflammatory Bowel Disease (IBD) is a persistent gastrointestinal (GI) tract
inflammatory disease characterized by downregulated mucosal immune activities and a …

[HTML][HTML] Antioxidant Therapy in Inflammatory Bowel Diseases: How Far Have We Come and How Close Are We?

LEMS Xavier, TCG Reis, ASP Martins, JCF Santos… - Antioxidants, 2024 - mdpi.com
Inflammatory bowel diseases (IBD) pose a growing public health challenge with unclear
etiology and limited efficacy of traditional pharmacological treatments. Alternative therapies …

Unveiling the phytochemical profile, in vitro bioactivities evaluation, in silico molecular docking and ADMET study of essential oil from Clinopodium nepeta grown in …

N Benkhaira, N El Hachlafi, M Jeddi, R Abdnim… - Biocatalysis and …, 2023 - Elsevier
Clinopodium nepeta is an aromatic species appertaining to the Lamiaceae family, and has
been mentioned for its numerous traditional uses and pharmacological properties …

Diosmin alleviates ulcerative colitis in mice by increasing Akkermansia muciniphila abundance, improving intestinal barrier function, and modulating the NF-κB and …

MB Salem, NM El-Lakkany, SHS El-Din, OA Hammam… - Heliyon, 2024 - cell.com
Ulcerative colitis is a common type of inflammatory bowel disease that affects millions of
individuals around the world. Traditional UC treatment has focused on suppressing immune …

[HTML][HTML] Canagliflozin-loaded chitosan-hyaluronic acid microspheres modulate AMPK/NF-κB/NLRP3 axis: A new paradigm in the rectal therapy of ulcerative colitis

M Nasr, S Cavalu, S Saber, ME Youssef… - Biomedicine & …, 2022 - Elsevier
Ulcerative colitis is an idiopathic disease that is widely incident worldwide. Canagliflozin,
antidiabetic agent, exhibited significant anti-inflammatory effects in a variety of animal …

Fexofenadine-loaded chitosan coated solid lipid nanoparticles (SLNs): A potential oral therapy for ulcerative colitis

WA El-Dakroury, MB Zewail, GF Asaad… - European Journal of …, 2024 - Elsevier
The targeting and mucoadhesive features of chitosan (CS)-linked solid lipid nanoparticles
(SLNs) were exploited to efficiently deliver fexofenadine (FEX) into the colon, forming a …

[HTML][HTML] Oral Macrocystis pyrifera Fucoidan Administration Exhibits Anti-Inflammatory and Antioxidant Properties and Improves DSS-Induced Colitis in C57BL/6J Mice

T Ahmad, M Ishaq, S Karpiniec, A Park, D Stringer… - Pharmaceutics, 2022 - mdpi.com
Inflammatory bowel disease (IBD) is a complex and multifactorial disorder characterised by
relapsing and remitting inflammation of the intestinal tract. Oxidative stress (OS) is the result …

[HTML][HTML] Anxiolytic and anti-colitis effects of Moringa oleifera leaf-aqueous extract on acetic acid-induced colon inflammation in rat

PA Noubissi, Q Njilifac, MAF Tagne… - Biomedicine & …, 2022 - Elsevier
Moringa oleifera decoction is believed to alleviate gastrointestinal tract diseases. This study
investigated antioxidant and anxiolytic activities of its leaves aqueous extract on acetic acid …

[HTML][HTML] Comparison of 5-ASA layered or matrix pellets coated with a combination of ethylcellulose and eudragits L and s in the treatment of ulcerative colitis in rats

HS Sardou, F Sadeghi, HA Garekani, A Akhgari… - International Journal of …, 2023 - Elsevier
The aim of this study was to evaluate and optimize the combination of time and pH-
dependent polymers as a single coating for the design of the colon-specific drug delivery …

Natural sources and pharmacological properties of santalenes and santalols

N El Hachlafi, N Benkhaira, I Mssillou… - Industrial Crops and …, 2024 - Elsevier
Santalum album L., commonly known as sandalwood, is a tree species with recognized
medicinal properties. The essential oil extracted from the heartwood of this tree is of …