Mammalian skeletal muscle shows an enormous variability in its functional features such as
rate of force production, resistance to fatigue, and energy metabolism, with a wide spectrum …

Research in the area of the pale, soft and exudative (PSE) pork and poultry meat is reviewed
in this article with an emphasis on genetic, biochemical and metabolic factors contributing to …

How is the heartbeat generated? What controls the strength of contraction of heart muscle?
What are the links between cardiac structure and function? How does our understanding of …

Malignant hyperthermia (MH) causes neurological, liver, and kidney damage and death in
humans and major economic losses in the swine industry. A single point mutation in the …

Pale, soft and exudative (PSE) pork represents considerable economic losses for the
industry due to its limited functionality and undesirable appearance. During the past several …

The ryanodine receptor (RyR) is a high-conductance Ca2+ channel of the sarcoplasmic
reticulum in muscle and of the endoplasmic reticulum in other cells. In striated muscle fibers …

Calcium (Ca2+) release from intracellular stores controls numerous cellular processes,
including cardiac and skeletal muscle contraction, synaptic transmission and metabolism …

The ryanodine receptor (RyR) c corresponds to the sarcoplasmic reticulum (SR) Ca2+
channel (Inui et al., 1987; Imagawa et al., 1987). Its structure and function have been …

Calcium-induced calcium release (CICR) was first discovered in skeletal muscle. CICR is
defined as Ca2+ release by the action of Ca2+ alone without the simultaneous action of …

MALIGNANT hyperthermia (MH) is a potentially lethal condition in which sustained muscle
contracture, with attendant hypercatabolic reactions and elevation in body temperature, are …