The Hierarchical Taxonomy of Psychopathology (HiTOP) is an empirical effort to address
limitations of traditional mental disorder diagnoses. These include arbitrary boundaries …

Objective The aim of this review was to investigate whether e-cigarette use compared with
non-use in young non-smokers is associated with subsequent cigarette smoking. Data …

The topic of e-cigarettes is controversial. Opponents focus on e-cigarettes' risks for young
people, while supporters emphasize the potential for e-cigarettes to assist smokers in …

Alcohol use disorder is a major contributor to the morbidity and mortality burden worldwide.
It often coexists with other psychiatric disorders; however, the nature of this comorbidity is …

E-cigarette use among US youth and young adults is now a major public health concern. E-
cigarette use has increased considerably in recent years, growing an astounding 900 …

Despite an estimated heritability of~ 50%, genome-wide association studies of opioid use
disorder (OUD) have revealed few genome-wide significant loci. We conducted a cross …

Background This systematic review of prospective longitudinal primary studies sought to
determine whether electronic cigarette (e-cigarette) use by teenagers who had never …

Inhalation of the toxic smoke produced by combusting tobacco products, primarily cigarettes,
is the overwhelming cause of tobacco-related disease and death in the United States and …

Background Alcohol, tobacco and marijuana are the most commonly used drugs by
adolescents in the US However, little is known about the patterning of early adolescent …

Purpose This review characterizes empirically derived patterns of multiple (multi-) substance
use among adolescents. A secondary objective was to examine the extent to which mental …